2
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Beliefs, awareness, use, and factors associated with herbal supplements usage among patients with chronic diseases–A cross-sectional insight from Alkharj, Saudi Arabia

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Background

          Herbal supplements (HSs) are used to treat a variety of diseases and ailments. Individuals with chronic diseases are at a higher risk of having adverse events and drug interactions from the use of HSs.

          Aim

          This study determined the beliefs, awareness, use, and factors associated with HSs usage among patients with chronic diseases in Alkharj, Saudi Arabia.

          Method

          A cross-sectional study was conducted among patients with chronic diseases between February and June 2019. Face-to-face interviews were conducted at various out-patient clinics in different hospitals. Patients diagnosed with chronic diseases were included in the study. Data were analyzed by descriptive, comparative, and inferential statistics using SAS ver. 9.4.

          Results

          The study participants were consisted of 533 patients, with mean age 53.6 ±12.9 years. The most prevalent chronic diseases were diabetes mellitus (67.7%), followed by hypertension (54.8%), and hyperlipidemia (53.8%). Among the studied participants, 336 (63%) had used at least one HS, whereby the most commonly used HSs were ginger (74.7%), mint (72%), and cumin (66.7%). Almost 78% of HSs users did not consult any healthcare provider about their use. HSs use varied significantly between female and male participants ( p<0.05), whereby 61.5% of female participants used HSs in comparison to the male participants (38.5%). Gender (AOR 0.328; 95% CI 0.139–0.772; p = 0.0107), number of chronic diseases (AOR 1.585; 95% CI 1.084–2.318; p = 0.0312), and hyperlipidemia (AOR 2.818; 95% CI 1.507–5.269; p = 0.0.0012) were the pure factors of HSs use among the studied patients.

          Conclusion

          The results of this study showed that HSs usage was high among patients with chronic diseases in Saudi Arabia. Concurrent usage of HSs with drugs should be well-discussed with healthcare providers to avoid potential adverse events or drug interactions especially among patients with chronic diseases.

          Related collections

          Most cited references37

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Sample Size Estimation in Clinical Trial

          Every clinical trial should be planned. This plan should include the objective of trial, primary and secondary end-point, method of collecting data, sample to be included, sample size with scientific justification, method of handling data, statistical methods and assumptions. This plan is termed as clinical trial protocol. One of the key aspects of this protocol is sample size estimation. The aim of this article is to discuss how important sample size estimation is for a clinical trial, and also to understand the effects of sample size over- estimation or under-estimation on outcome of a trial. Also an attempt is made to understand importance of minimum sample to detect a clinically important difference. This article is also an attempt to provide inputs on different parameters that impact sample size and basic rules for these parameters with the help of some simple examples.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety

            Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing prevalence. They remain the leading causes of morbidity and mortality worldwide. The use of medicinal herbs continues to be an alternative treatment approach for several diseases including CVDs. Currently, there is an unprecedented drive for the use of herbal preparations in modern medicinal systems. This drive is powered by several aspects, prime among which are their cost-effective therapeutic promise compared to standard modern therapies and the general belief that they are safe. Nonetheless, the claimed safety of herbal preparations yet remains to be properly tested. Consequently, public awareness should be raised regarding medicinal herbs safety, toxicity, potentially life-threatening adverse effects, and possible herb–drug interactions. Over the years, laboratory data have shown that medicinal herbs may have therapeutic value in CVDs as they can interfere with several CVD risk factors. Accordingly, there have been many attempts to move studies on medicinal herbs from the bench to the bedside, in order to effectively employ herbs in CVD treatments. In this review, we introduce CVDs and their risk factors. Then we overview the use of herbs for disease treatment in general and CVDs in particular. Further, data on the ethnopharmacological therapeutic potentials and medicinal properties against CVDs of four widely used plants, namely Ginseng, Ginkgo biloba, Ganoderma lucidum, and Gynostemma pentaphyllum, are gathered and reviewed. In particular, the employment of these four plants in the context of CVDs, such as myocardial infarction, hypertension, peripheral vascular diseases, coronary heart disease, cardiomyopathies, and dyslipidemias has been reviewed, analyzed, and critically discussed. We also endeavor to document the recent studies aimed to dissect the cellular and molecular cardio-protective mechanisms of the four plants, using recently reported in vitro and in vivo studies. Finally, we reviewed and reported the results of the recent clinical trials that have been conducted using these four medicinal herbs with special emphasis on their efficacy, safety, and toxicity.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Why people use herbal medicine: insights from a focus-group study in Germany

              Background The use of herbal medicine, as one element of complementary and alternative medicine, is increasing worldwide. Little is known about the reasons for and factors associated with its use. This study derives insights for the use of herbal medicine in Germany regarding the usage aims, role played by the type of illness, reasons for preferred usage and sources of information. Methods Using a qualitative methodological approach, six focus groups (n = 46) were conducted. Two groups with young, middle-aged and elderly participants, respectively. After audiotaping and verbatim transcription, the data were analysed with a qualitative content analysis. Results We found that treating illnesses was the most frequently discussed aim for using herbal medicine over all age groups. Preventing illnesses and promoting health were less frequently mentioned overall, but were important for elderly people. Discussions on herbal medicine were associated with either mild/moderate diseases or using herbal medicine as a starting treatment before applying conventional medicine. In this context, participants emphasized the limits of herbal medicine for severe illnesses. Dissatisfaction with conventional treatment, past good experiences, positive aspects associated with herbal medicine, as well as family traditions were the most commonly-mentioned reasons why herbal medicine was preferred as treatment. Concerning information sources, independent reading and family traditions were found to be equally or even more important than consulting medicinal experts. Conclusions Although herbal medicine is used mostly for treating mild to moderate illnesses and participants were aware of its limits, the combination of self-medication, non-expert consultation and missing risk awareness of herbal medicine is potentially harmful. This is particularly relevant for elderly users as, even though they appeared to be more aware of health-related issues, they generally use more medicine compared to younger ones. In light of our finding that dissatisfaction with conventional medicine was the most important reason for a preferred use of herbal medicine, government bodies, doctors, and pharmaceutical companies need to be aware of this problem and should aim to establish a certain level of awareness among users concerning this issue. Electronic supplementary material The online version of this article (10.1186/s12906-018-2160-6) contains supplementary material, which is available to authorized users.
                Bookmark

                Author and article information

                Contributors
                Role: Data curationRole: Project administrationRole: SupervisionRole: Writing – original draft
                Role: Data curation
                Role: Data curation
                Role: Data curation
                Role: Formal analysisRole: Methodology
                Role: Formal analysisRole: Methodology
                Role: Data curationRole: Investigation
                Role: Formal analysisRole: MethodologyRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS One
                plos
                PLOS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                17 January 2024
                2024
                : 19
                : 1
                : e0295116
                Affiliations
                [1 ] Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
                [2 ] Pharmaceutical Care Services, King Fahad Specialist Hospital, Buraydah, Saudi Arabia
                [3 ] Pharmacy Department, General Directorate of Medical Services, Ministry of Interior, Al-Kharj, Saudi Arabia
                [4 ] Pharmacy Department, Al-Kharj Military Industries Corporation Hospital, Al-Kharj, Saudi Arabia
                [5 ] Department of Ophthalmology, Al-Kharj Military Industries Corporation Hospital, Al-Kharj, Saudi Arabia
                National University of Science and Technology, ZIMBABWE
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                https://orcid.org/0000-0002-9130-1639
                https://orcid.org/0000-0003-0245-5976
                Article
                PONE-D-22-35344
                10.1371/journal.pone.0295116
                10793931
                38232068
                0ae2ffad-8439-43ce-b29b-60d461ecadd4
                © 2024 Albassam et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 26 December 2022
                : 14 November 2023
                Page count
                Figures: 1, Tables: 5, Pages: 13
                Funding
                This study is supported via funding from Prince Sattam bin Abdulaziz University project number (PSAU/2023/R/1444).
                Categories
                Research Article
                Medicine and Health Sciences
                Health Care
                Health Care Providers
                Research and Analysis Methods
                Research Design
                Clinical Research Design
                Adverse Events
                Medicine and Health Sciences
                Clinical Medicine
                Signs and Symptoms
                Hyperlipidemia
                Medicine and Health Sciences
                Pharmacology
                Drug Interactions
                Medicine and Health Sciences
                Medical Conditions
                Cardiovascular Diseases
                Medicine and Health Sciences
                Cardiology
                Cardiovascular Medicine
                Cardiovascular Diseases
                Medicine and Health Sciences
                Medical Conditions
                Respiratory Disorders
                Asthma
                Medicine and Health Sciences
                Pulmonology
                Respiratory Disorders
                Asthma
                People and places
                Geographical locations
                Asia
                Saudi Arabia
                Medicine and Health Sciences
                Health Care
                Patients
                Custom metadata
                Data is present inside the paper.

                Uncategorized
                Uncategorized

                Comments

                Comment on this article