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      The effects of topical application of sunflower-seed oil on open wound healing in lambs Translated title: Efeitos da aplicação tópica de óleo de semente de girassol em feridas cutâneas, em carneiros

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          Abstract

          PURPOSE: To demonstrate the effects of the use of sunflower seed oil on the treatment of skin wounds. METHODS: Eighteen male Saint Inês lambs were divided in 3 groups according to the pos-operative (7, 14 and 21 days). After antisepsis and local anestesia, two 4cm² wounds on each side of the thoracic region, close to the scapule were surgically produced. The experimental wounds were treated with sunflower seed oil, with high concentration of linoleic acid (LA), and the control ones with sterilized Vaseline. Biopsies of the pos-operative wounds tissue were performed on the 7th, 14th, 21st days and histologically evaluated. RESULTS: Topic application of sunflower seed oil accelerated healing process at the 7th and 21st days, reducing wound area and increasing wound contraction. Granulation tissue increased faster on treated wounds. The epidermis of the treated wounds was completely recovered when compared to control wounds. CONCLUSION: The topic use of sunflower seed oil accelerated the healing process, and it can be used as an alternative therapy on second intention wound healing.

          Translated abstract

          OBJETIVO: Demonstrar os efeitos do uso de óleo de semente de girassol no tratamento de feridas cutâneas. MÉTODOS: Dezoito carneiros da raça Santa Inês foram divididos em 3 grupos de acordo com o pós-cirúrgico (7, 14, e 21 dias). Após antisepsia e anestesia local foram produzidas cirurgicamente duas feridas de 4 cm² em cada lado da região torácica próxima escápula. As feridas experimentais foram tratadas com óleo de semente de girassol, com alta concentração de ácido linoléico (LA) e as controles com vaselina esterilizada. Biopsias dos tecidos das feridas pós-cirúrgicas foram realizadas no 7º, 14º e 21º dias e avaliadas histologicamente. RESULTADOS: A aplicação tópica do óleo de semente de girassol acelerou o processo de cicatrização no 7ºe 21º dias, reduzindo a área e aumentando a contração das feridas. O tecido de granulação se desenvolveu mais rapidamente em feridas tratadas. A epiderme das feridas tratadas estava completamente reconstituída em relação às feridas controle. CONCLUSÃO: O uso tópico do óleo de semente de girassol acelerou a cicatrização, podendo ser utilizado como alternativa terapêutica na cicatrização de feridas por segunda intenção.

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          Nutritional role of polyunsaturated fatty acids

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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                acb
                Acta Cirurgica Brasileira
                Acta Cir. Bras.
                Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (São Paulo )
                1678-2674
                June 2004
                : 19
                : 3
                : 196-209
                Affiliations
                [1 ] Universidade Federal Rural de Pernambuco Brazil
                [2 ] Universidade Federal Rural de Pernambuco Brazil
                [3 ] Universidade Federal de Pernambuco Brazil
                [4 ] Universidade Federal Rural de Pernambuco Brazil
                Article
                S0102-86502004000300005
                10.1590/S0102-86502004000300005
                0a0a633d-4816-4517-9a60-574efe21c547

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=0102-8650&lng=en
                Categories
                SURGERY

                Surgery
                Sunflower-seed oil,Topic use,Wound healing,Óleo de semente de girassol,Uso tópico,Cicatrização de feridas

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