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      A ten-year review of the impact of the transition from warfarin to direct oral anticoagulant - Has venous thromboembolism treatment become safer?

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          Abstract

          The introduction of direct oral anticoagulants (DOAC) has resulted in a paradigm shift in the management of venous thromboembolism (VTE). We evaluate the impact of the transition to DOAC, over the last decade, on overall VTE clinical outcomes including in first unprovoked major VTEs.

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          Author and article information

          Journal
          Thromb Res
          Thrombosis research
          Elsevier BV
          1879-2472
          0049-3848
          Nov 2022
          : 219
          Affiliations
          [1 ] Department of Haematology, Northern Health, Epping, VIC, Australia. Electronic address: brandon.lui@nh.org.au.
          [2 ] Department of Haematology, Northern Health, Epping, VIC, Australia.
          [3 ] Department of Pharmacy, Northern Health, Epping, VIC, Australia.
          [4 ] Department of Haematology, Northern Health, Epping, VIC, Australia; Department of Medicine (Northern Health), University of Melbourne, Heidelberg, VIC, Australia.
          Article
          S0049-3848(22)00386-3
          10.1016/j.thromres.2022.09.006
          36162254
          08a13fec-bf0e-4ef7-86f4-b06ff2b8c8e8
          History

          Bleeding,Anticoagulants,Thrombosis,Venous thromboembolism

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