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      Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid.

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          Abstract

          Shaoyao-Gancao Decoction (SGD), a well-known traditional Chinese medicine prescription, is a combination of Radix Paeoniae Alba (Paeonia lactiflora Pall, root) and Glycyrrhizae uralensis (Glycyrrhiza uralensis Fisch., root and rhizome, honeyed) for spasmolysis and emergency pain relief. Paeoniflorin (PF) and glycyrrhetinic acid (GA) are two typical active components of SGD for pain relief.

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          Author and article information

          Journal
          J Ethnopharmacol
          Journal of ethnopharmacology
          Elsevier BV
          1872-7573
          0378-8741
          Sep 16 2013
          : 149
          : 2
          Affiliations
          [1 ] Department of Chemistry, Tsinghua University, Beijing 100084, PR China. xuchanghua@gmail.com
          Article
          S0378-8741(13)00482-0
          10.1016/j.jep.2013.06.049
          23867078
          08182ca6-2e73-476c-81eb-b2b355c16de5
          © 2013 Elsevier Ireland Ltd. All rights reserved.
          History

          GA,GU,GZ,Glycyrrhetinic acid,Glycyrrhizae uralensis,HM,HPLC-MS/MS,PF,Paeoniflorin,RP,Radix Paeoniae Alba,SGD,Shaoyao-Gancao Decoction,glycyrrhenitic acid,glycyrrhizin,herbal medicine,paeoniflorin

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