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      Expression Profiles of CDKN2A, MDM2, E2F2 and LTF Genes in Oral Squamous Cell Carcinoma.

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          Abstract

          Oral squamous cell carcinoma (OSCC) is one of the most commonly detected neoplasms worldwide. Not all mechanisms associated with cell cycle disturbances are known in OSCC. Examples of genes involved in the control of the cell cycle are CDKN2A, MDM2, E2F2 and LTF. The aim of this study was to examine the possible association between CDKN2A, MDM2, E2F2 and LTF mRNA expression and influence on clinical variables.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Biomedicines
          Title: Biomedicines
          Publisher: MDPI AG
          ISSN: 2227-9059
          ISSN (Print): 2227-9059
          Publication date (Electronic): Nov 23 2022
          Volume: 10
          Issue: 12
          Affiliations
          [1 ] Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana Str., 41-808 Zabrze, Poland.
          [2 ] Department of Forest Management Planning, Poznań University of Life Sciences, 71 C Wojska Polskiego Str., 60-625 Poznan, Poland.
          [3 ] Department of Otorhinolaryngology and Oncological Laryngology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 10 C Skłodowskiej Str., 41-800 Zabrze, Poland.
          [4 ] Clinic of Oncological and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, 15 Wybrzeże Armii Krajowej Str., 44-102 Gliwice, Poland.
          Article
          Publisher Item ID: biomedicines10123011
          DOI: 10.3390/biomedicines10123011
          PMC ID: 9775533
          PubMed ID: 36551770
          SO-VID: 072b6fa7-5215-4158-9c83-5d37642c8cd1
          History

          Keywords: CDKN2A,oral squamous cell carcinoma,gene expression,cancer,MDM2,LTF,E2F2
          Data availability:
          Keywords: CDKN2A, oral squamous cell carcinoma, gene expression, cancer, MDM2, LTF, E2F2

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