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      A small difference in recovery between total knee arthroplasty with and without tourniquet use the first 3 months after surgery: a randomized controlled study

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          Abstract

          Purpose

          When a tourniquet is used during surgery on the extremities, the pressure applied to the muscles, nerves and blood vessels can cause neuromuscular damage that contributes to postoperative weakness. The hypothesis was that the rehabilitation-related results would be improved if total knee arthroplasty (TKA) is performed without the use of a tourniquet.

          Methods

          81 patients with osteoarthritis of the knee who underwent TKA surgery were randomized to surgery with or without tourniquet. Active flexion and extension of the knee, pain by visual analog scale (VAS), swelling by knee circumference, quadriceps function by straight leg raise, and timed up and go (TUG) test results were measured before and up to 3 months after surgery.

          Results

          ANCOVA revealed no between-groups effect for flexion of the knee at day 3 postsurgery. Compared with the tourniquet group, the nontourniquet group experienced elevated pain at 24 h, with a mean difference of 16.6 mm, p = 0.005. The effect on mobility (TUG test) at 3 months was better in the nontourniquet group, with a mean difference of -1.1 s, p = 0.029.

          Conclusions

          The hypothesis that the rehabilitation-related results would be improved without a tourniquet is not supported by the results. When the results in this study for surgery performed with and without tourniquet are compared, no clear benefit for either procedure was observed, as the more pain exhibited by the nontourniquet group was only evident for a short period and the improved mobility in this group was not at a clinically relevant level.

          Level of evidence

          Inconsistent results, Level II.

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          Most cited references33

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          Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis.

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            Does Tourniquet Use in TKA Affect Recovery of Lower Extremity Strength and Function? A Randomized Trial.

            Tourniquet use during total knee arthroplasty (TKA) improves visibility and reduces intraoperative blood loss. However, tourniquet use may also have a negative impact on early recovery of muscle strength and lower extremity function after TKA.
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              Anesthetic, patient, and surgical risk factors for neurologic complications after prolonged total tourniquet time during total knee arthroplasty.

              Nerve injury after prolonged tourniquet inflation results from the combined effects of ischemia and mechanical trauma. Tourniquet release, allowing a reperfusion interval of 10-30 min followed by re-inflation, has been recommended to extend the duration of total tourniquet time. However, this practice has not been confirmed clinically. We retrospectively reviewed the medical records of 1001 patients undergoing 1166 primary or revision knee replacements with tourniquet time more than 120 min during a 5-yr interval. Mean total tourniquet time was 145 +/- 25 min (range, 120-308 min). In 759 patients, the tourniquet inflation was uninterrupted. Two tourniquet inflations, interrupted by a single deflation, were noted in 371 patients, and 3 tourniquet inflations interrupted by 2 deflation intervals were noted in 23 patients. A total of 129 neurologic complications (peroneal and/or tibial nerve palsies) were noted in 90 patients for an overall incidence of 7.7%. Eighty-five cases involved the peroneal nerve and 44 cases involved the tibial nerve. In 39 cases, both peroneal and tibial deficits were noted. Complete neurologic recovery occurred in 76 (89%) peroneal and 44 (100%) tibial palsies. Postoperative neurologic dysfunction was associated with younger age (P 20 degrees (P = 0.002; odds ratio = 3.9). In a subset of 116 patients with tourniquet times > or =180 min, longer duration of deflation was associated with a decreased frequency of neurologic complications (P = 0.048). We conclude that the likelihood of neurologic dysfunction increases with total tourniquet time and that a reperfusion interval only modestly decreases the risk of nerve injury.
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                Author and article information

                Contributors
                0046 16 10 52 51 , 0046 73 949 99 33 , Staffankarldavid.eriksson@dll.se
                Journal
                Knee Surg Sports Traumatol Arthrosc
                Knee Surg Sports Traumatol Arthrosc
                Knee Surgery, Sports Traumatology, Arthroscopy
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                0942-2056
                1433-7347
                17 October 2018
                17 October 2018
                2019
                : 27
                : 4
                : 1035-1042
                Affiliations
                [1 ]Department of Orthopedics, Nyköping Hospital, 611 85 Nyköping, Sweden
                [2 ]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Centre for Clinical Research Sörmland, , Uppsala University, ; Kungsgatan 41, 631 88 Eskilstuna, Sweden
                [3 ]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Department of Surgical Sciences, , Uppsala University, ; 751 85 Uppsala, Sweden
                [4 ]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Department of Neuroscience, Physiotherapy, , Uppsala University, ; Box 593, 751 24 Uppsala, Sweden
                [5 ]ISNI 0000 0001 1034 3451, GRID grid.12650.30, Department of Community Medicine and Rehabilitation, Physiotherapy, , Umeå University, ; 901 87 Umeå, Sweden
                Article
                5196
                10.1007/s00167-018-5196-8
                6435610
                30328495
                072288e6-0834-4654-9847-e735675b0c6a
                © The Author(s) 2018

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 7 March 2018
                : 2 October 2018
                Categories
                Knee
                Custom metadata
                © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019

                Surgery
                total knee arthroplasty,tourniquet,rehabilitation,surgery
                Surgery
                total knee arthroplasty, tourniquet, rehabilitation, surgery

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