miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients.

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Abstract

The proper validation of prognostic biomarkers is an important clinical issue in breast cancer research. MicroRNAs (miRNAs) have emerged as a new class of promising breast cancer biomarkers. In the present work, we developed an integrated online bioinformatic tool to validate the prognostic relevance of miRNAs in breast cancer.

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Journal

Journal ID (iso-abbrev): Breast Cancer Res. Treat.

Title: Breast cancer research and treatment

Publisher: Springer Nature

ISSN (Electronic): 1573-7217

ISSN (Print): 0167-6806

Publication date (Electronic): Dec 2016

Volume: 160

Issue: 3

Affiliations

[1 ] MTA TTK Lendület Cancer Biomarker Research Group, Magyar Tudósok körútja 2, Budapest, 1117, Hungary.

[2 ] Department of Pediatrics, Semmelweis University, Budapest, Hungary.

[3 ] Oncology Experimental Therapeutics Unit, Humanitas Clinical and Research Institute, Via Manzoni 113, 20089, Rozzano-Milan, Italy.

[4 ] MTA-SE Pediatrics and Nephrology Research Group, Budapest, Hungary.

[5 ] Oncology Experimental Therapeutics Unit, Humanitas Clinical and Research Institute, Via Manzoni 113, 20089, Rozzano-Milan, Italy. libero.santarpia@humanitasresearch.it.

[6 ] MTA TTK Lendület Cancer Biomarker Research Group, Magyar Tudósok körútja 2, Budapest, 1117, Hungary. gyorffy.balazs@ttk.mta.hu.

[7 ] Department of Pediatrics, Semmelweis University, Budapest, Hungary. gyorffy.balazs@ttk.mta.hu.

Article

Publisher Item ID: 10.1007/s10549-016-4013-7

DOI: 10.1007/s10549-016-4013-7

PubMed ID: 27744485

SO-VID: 070ceb9c-5414-49c5-ab2e-2aa530599214

History

Keywords: Biomarkers,Breast cancer,Gene expression,MicroRNAs,Prognosis,Survival

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Keywords: Biomarkers, Breast cancer, Gene expression, MicroRNAs, Prognosis, Survival

miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients.

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Karger: Oncology

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