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      Amplitude envelope correlation detects coupling among incoherent brain signals.

      Neuroreport
      Adult, Cognition, physiology, Cortical Synchronization, standards, Female, Humans, Male, Photic Stimulation, Psychophysics, Reproducibility of Results, Visual Cortex

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          Abstract

          Cognitive processing involves gamma-activation over broad cortical regions. Phase coupling of these activities has rarely been reported for areas far apart. Other forms of coupling are generally not detected by conventional measures. Here, we use amplitude envelope correlation (AEC), which can detect signal coupling without phase coherence, even among different frequencies. We apply it to subdural recordings from humans performing a visual delayed match-to-sample task and systematically compare it with spectral amplitude and coherence. The different measures often show divergent results. In particular, AEC reveals y-coupling completely missed by coherence. We argue that coherence and AEC are adapted to different cortical mechanisms of short- and long-range interactions, respectively.

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          Author and article information

          Journal
          10841367
          10.1097/00001756-200005150-00029

          Chemistry
          Adult,Cognition,physiology,Cortical Synchronization,standards,Female,Humans,Male,Photic Stimulation,Psychophysics,Reproducibility of Results,Visual Cortex

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