DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status.

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Abstract

The Dynamic International Prognostic Scoring System (DIPSS) for primary myelofibrosis (PMF) uses five risk factors to predict survival: age older than 65 years, hemoglobin lower than 10 g/dL, leukocytes higher than 25 × 10(9)/L, circulating blasts ≥ 1%, and constitutional symptoms. The main objective of this study was to refine DIPSS by incorporating prognostic information from karyotype, platelet count, and transfusion status.

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Journal

Journal ID (iso-abbrev): J Clin Oncol

Title: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Publisher: American Society of Clinical Oncology (ASCO)

ISSN (Electronic): 1527-7755

ISSN (Print): 0732-183X

Publication date (Electronic): Feb 01 2011

Volume: 29

Issue: 4

Affiliations

[1 ] Mayo Clinic, Rochester, MN 55905, USA.

Article

Publisher Item ID: JCO.2010.32.2446

DOI: 10.1200/JCO.2010.32.2446

PubMed ID: 21149668

SO-VID: 065b5ba3-f9b8-49d2-8024-3ff6944ee134

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