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      Stress distribution patterns during the gait cycle in patients with anterior femoral notching following total knee replacement

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          Abstract

          Background

          Anterior femoral notching ( AFN) is a severe complication of total knee replacement ( TKR), which in a percentage of patients may lead to fractures after surgery. The purpose of this study was to investigate the stress distribution in patients with AFN and the safety depth of AFN during the gait cycle.

          Methods

          We performed a finite element ( FE) analysis to analyse the mechanics around the femur during the gait cycle in patients with AFN. An adult volunteer was selected as the basis of the model. The TKR models were established in the 3D reconstruction software to simulate the AFN model during the TKR process, and the 1 mm, 2 mm, 3 mm, 4 mm, and 5 mm AFN models were established, after which the prosthesis was assembled. Three key points of the gait cycle (0°, 22°, and 48°) were selected for the analysis.

          Results

          The stress on each osteotomy surface was stable in the 0° phase. In the 22° phase, the maximum equivalent stress at 3 mm was observed. In the 48° phase, with the increase in notch depth, each osteotomy surface showed an overall increasing trend, the stress range was more extended, and the stress was more concentrated. Moreover, the maximum equivalent force value (158.3 MPa) exceeded the yield strength (115.1 MPa) of the femur when the depth of the notch was ≥ 3 mm.

          Conclusions

          During the gait cycle, if there is an anterior femoral cortical notch ≥ 3 mm, the stress will be significantly increased, especially at 22° and 48°. The maximum equivalent stress exceeded the femoral yield strength and may increase the risk of periprosthetic fractures.

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          Most cited references31

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          Bone Mechanical Properties in Healthy and Diseased States

          The mechanical properties of bone are fundamental to the ability of our skeletons to support movement and to provide protection to our vital organs. As such, deterioration in mechanical behavior with aging and/or diseases such as osteoporosis and diabetes can have profound consequences for individuals’ quality of life. This article reviews current knowledge of the basic mechanical behavior of bone at length scales ranging from hundreds of nanometers to tens of centimeters. We present the basic tenets of bone mechanics and connect them to some of the arcs of research that have brought the field to recent advances. We also discuss cortical bone, trabecular bone, and whole bones, as well as multiple aspects of material behavior, including elasticity, yield, fracture, fatigue, and damage. We describe the roles of bone quantity (e.g., density, porosity) and bone quality (e.g., cross-linking, protein composition), along with several avenues of future research.
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            Hip joint loading during walking and running, measured in two patients.

            The resultant hip joint force, its orientation and the moments were measured in two patients during walking and running using telemetering total hip prostheses. One patient underwent bilateral joint replacement and a second patient, additionally suffering from a neuropathic disease and atactic gait patterns, received one instrumented hip implant. The joint loading was observed over the first 30 and 18 months, respectively, following implantation. In the first patient the median peak forces increased with the walking speed from about 280% of the patient's body weight (BW) at 1 km h-1 to approximately 480% BW at 5 km h-1. Jogging and very fast walking both raised the forces to about 550% BW; stumbling on one occasion caused magnitudes of 720% BW. In the second patient median forces at 3 km h-1 were about 410% BW and a force of 870% BW was observed during stumbling. During all types of activities, the direction of the peak force in the frontal plane changed only slightly when the force magnitude was high. Perpendicular to the long femoral axis, the peak force acted predominantly from medial to lateral. The component from ventral to dorsal increased at higher force magnitudes. In one hip in the first patient and in the second patient the direction of large forces approximated the average anteversion of the natural femur. The torsional moments around the stem of the implant were 40.3 N m in the first patient and 24 N m in the second.
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              The forces in the distal femur and the knee during walking and other activities measured by telemetry.

              The forces and moments in the shaft of a distal femoral replacement were measured by telemetry for a subject during different activities, and calculations were then made of the forces at the knee. The axial force showed a small peak at heel-strike followed by two main peaks during stance. In level walking, the peak axial force was between 1,487 and 1,718 N (2.2-2.5 BW), the peak shear force was 269-368 N (0.4-0.54 BW) directed anteriorly on the tibia, the peak axial torque was 7 Nm internal, while the patellofemoral force was 466-571 N. The highest axial force was recorded for descending stairs (2.8 BW). Standing on one leg produced 2.4 BW, while lying supine and raising the leg produced 1.7 BW. The data produced may resemble that of a normal subject, and has application to basic joint mechanics, to joint reconstruction, and to total knee replacement design and evaluation.
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                Author and article information

                Contributors
                982869723@qq.com
                908408014@qq.com
                615898830@qq.com
                1748233624@qq.com
                798131672@qq.com
                xzchenxiangyang@163.com
                xzfs0561@163.com
                Journal
                BMC Musculoskelet Disord
                BMC Musculoskelet Disord
                BMC Musculoskeletal Disorders
                BioMed Central (London )
                1471-2474
                28 July 2022
                28 July 2022
                2022
                : 23
                : 718
                Affiliations
                GRID grid.413389.4, ISNI 0000 0004 1758 1622, Department of Orthopedic Surgery, , Affiliated Hospital of Xuzhou Medical University, ; 99 Huaihai Road, 221002 Xuzhou, Jiangsu China
                Article
                5643
                10.1186/s12891-022-05643-9
                9330681
                05b99ab3-e42f-4005-9c33-8c0fc5dda7e2
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 8 March 2022
                : 11 July 2022
                Funding
                Funded by: the Jiangsu Commission of Health
                Award ID: LX2021010
                Award ID: LX2021010
                Award ID: LX2021010
                Award ID: LX2021010
                Award ID: LX2021010
                Award ID: LX2021010
                Award ID: LX2021010
                Categories
                Research
                Custom metadata
                © The Author(s) 2022

                Orthopedics
                total knee replacement,finite element analysis,anterior femoral notching,gait cycle,biomechanics

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