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      Light in Gold Catalysis

      1 , 1 , 2 , 3
      Chemical Reviews
      American Chemical Society (ACS)

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          Most cited references249

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          Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis.

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            Fluorine in medicinal chemistry.

            It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.
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              Organic Photoredox Catalysis.

              In this review, we highlight the use of organic photoredox catalysts in a myriad of synthetic transformations with a range of applications. This overview is arranged by catalyst class where the photophysics and electrochemical characteristics of each is discussed to underscore the differences and advantages to each type of single electron redox agent. We highlight both net reductive and oxidative as well as redox neutral transformations that can be accomplished using purely organic photoredox-active catalysts. An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.
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                Author and article information

                Contributors
                (View ORCID Profile)
                (View ORCID Profile)
                Journal
                Chemical Reviews
                Chem. Rev.
                American Chemical Society (ACS)
                0009-2665
                1520-6890
                January 25 2021
                Affiliations
                [1 ]Organisch-Chemisches Institut, Heidelberg University, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany
                [2 ]Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia
                [3 ]State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
                Article
                10.1021/acs.chemrev.0c00841
                33492123
                058e1ea2-07b9-4f85-9ac1-4ee355169e6d
                © 2021
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