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      Surgical aspects of pneumatosis cystoides intestinalis: two case reports

      case-report
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      Cases Journal
      Cases Network Ltd

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          Abstract

          Introduction

          Pneumatosis cystoides intestinalis is a rare disease usually caused by an underlying condition. It is defined as air filled cysts within the wall of the gastrointestinal tract. The purpose of this paper is the development of an algorithm for the surgical therapy of PCI based one two case reports.

          Case presentations

          A 17-year-old girl with Down syndrome and leucopenia due to chemotherapy for acute lymphatic leukemia was admitted with acute septic conditions and PCI. Explorative laparotomy revealed acute ischemia of the right colon and resection of the affected intestine was performed. After a short interval in the intensive care unit the patient was referred to the pediatric department. The second patient, a 79 year old man, with urothelial carcinoma and carcinoma of the prostate presented a distended abdomen. CT-scan revealed PCI and adhesive strangulation of intestines. Therefore only adhesiolysis was performed and PCI was treated conservatively.

          Conclusion

          Only patients with increased inflammatory parameters in laboratory findings or signs of sepsis, peritonitis or bowel perforation in combination with PCI should receive an explorative laparotomy.

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          Most cited references18

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          The spectrum of pneumatosis intestinalis.

          A review of the spectrum of illness associated with pneumatosis intestinalis enables us to identify the probable causes of, the best diagnostic approaches to, and the most appropriate treatments for this condition. A review of all published material in the English language regarding pneumatosis intestinalis was conducted using the PubMed and MEDLINE databases. Any relevant work referenced in those articles and not previously found or published before the limit of the search engine was also retrieved and reviewed. There were no exclusion criteria for published information relevant to the topic. All of the studies cited in the present review make a point that contributes to the portrayal of this condition. In circumstances in which the same point was made in several different studies, not all were cited herein. All published material on pneumatosis intestinalis was considered. Information was extracted for preferentially selected ideas and theories supported in multiple studies. The collected information was organized by theory. Mucosal integrity, intraluminal pressure, bacterial flora, and intraluminal gas all interact in the formation of pneumatosis intestinalis. Radiography and computed tomography are the best diagnostic tests. Nonoperative management should be pursued in most patients, and underlying illnesses should be treated. When acute complications appear, such as perforation, peritonitis, and necrotic bowel, surgery is indicated.
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            Pneumatosis intestinalis. Surgical management and clinical outcome.

            Pneumatosis intestinalis (PI) occurs in a wide variety of patients, some of whom require urgent surgery, while others can be observed with resolution of symptoms and radiographic findings. During 1 year, 27 patients with PI were prospectively evaluated for clinical, laboratory, and radiographic features that would be useful in predicting the need for surgery, the pathologic findings, and patient outcome. Sixteen of the twenty-seven patients underwent laparotomy, with only one negative exploration. Of the 11 patients not explored, there were two deaths in moribund patients. Seven of nine patients with jejunostomy tubes, recent gastrointestinal anastomoses, inflammatory bowel disease, lactulose therapy, or chemotherapy who did not have clinical evidence of an acute surgical abdomen or metabolic acidosis survived without surgery (two deaths unrelated to the gastrointestinal tract). Patients presenting with bowel obstruction and PI required surgery in seven of nine cases, did not have necrotic bowel, and had 11% mortality. Eight patients with ischemic bowel had a 75% mortality rate, despite surgery. Patients with PI and clinical evidence of bowel obstruction or ischemia usually require urgent surgery, while asymptomatic patients without metabolic acidosis can be safely observed.
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              Abdominal gas cysts (pneumatosis cystoides intestinorum hominis); an analysis with a report of a case and a critical review of the literature.

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                Author and article information

                Journal
                Cases J
                Cases Journal
                Cases Network Ltd
                1757-1626
                12 August 2009
                2009
                : 2
                : 6452
                Affiliations
                [1]simpleDepartment of General, Visceral, Vascular and Transplant-Surgery, Julius-Maximilians-University of Würzburg WürzburgGermany
                Article
                6452
                10.4076/1757-1626-2-6452
                2769295
                19918585
                051fae49-f386-4b12-b287-9e44c0c88bd5
                © 2009 Schröpfer and Meyer; licensee Cases Network Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 09 March 2009
                : 17 July 2009
                Categories
                Case report

                Medicine
                Medicine

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