Journal ID (nlm-ta): PLoS Genet
Journal ID (iso-abbrev): PLoS Genet
Journal ID (publisher-id): plos
Journal ID (pmc): plosgen
Title:
PLoS Genetics
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7390
ISSN
(Electronic):
1553-7404
Publication date
(Electronic):
19
May
2016
Publication date Collection:
May
2016
Volume: 12
Issue: 5
Electronic Location Identifier: e1006054
Affiliations
[1
]Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United
States of America
[2
]Markey Cancer Center and Department of Molecular and Cellular Biochemistry, University
of Kentucky, Lexington, Kentucky, United States of America
[3
]Institute of Neuroscience, University of Oregon, Eugene, Oregon, United States of
America
[4
]Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas,
United States of America
[5
]Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston,
Texas, United States of America
[6
]Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United
States of America
[7
]Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston,
Texas, United States of America
[8
]Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, United
States of America
[9
]Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States
of America
New York University, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Conceived and designed the experiments: TL JF BBS NG JZ MTL AKG MW JJ HJB. Performed
the experiments: TL JF BBS NG GL SY MJ KC JZ WW. Analyzed the data: TL JF BBS NG KC
JZ JJ HJB. Contributed reagents/materials/analysis tools: WW MTL. Wrote the paper:
TL BBS GL SY MJ AKG MW JJ HJB.
Author information
Article
Publisher ID:
PGENETICS-D-15-03019
DOI: 10.1371/journal.pgen.1006054
PMC ID: 4873228
PubMed ID: 27195754
SO-VID: 044eb3d1-b982-4927-85fe-f5951359537f
Copyright © © 2016 Li et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000005, U.S. Department of Defense;
Award ID: W81XWH-11-1-0093
Award Recipient
:
Wei Wei
Funded by: funder-id http://dx.doi.org/10.13039/100000071, National Institute of Child Health and Human Development;
Award ID: 1U54 HD083092
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: GM079684
Award Recipient
:
Jianhang Jia
Funded by: funder-id http://dx.doi.org/10.13039/100007856, Baylor College of Medicine;
Award ID: P30 CA125123
Award Recipient
:
Michael T. Lewis
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: U54 CA149196
Award Recipient
:
Michael T. Lewis
Funded by: Breast Cancer SPORE
Award ID: P50 CA50183
Award Recipient
:
Michael T. Lewis
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: DC010987
Award Recipient
:
Andrew K. Groves
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: 1RC4GM096355-01
Award Recipient
:
Hugo J. Bellen
Funded by: the Robert and Renee Belfer Family Foundation
Award Recipient
:
Hugo J. Bellen
Funded by: the Huffington Foundation
Award Recipient
:
Hugo J. Bellen
Funded by: Target ALS
Award Recipient
:
Hugo J. Bellen
Funded by: funder-id http://dx.doi.org/10.13039/100000071, National Institute of Child Health and Human Development;
Award ID: P01 HD22486
Award Recipient
:
Monte Westerfield
Funded by: funder-id http://dx.doi.org/10.13039/100000055, National Institute on Deafness and Other Communication Disorders;
Award ID: R01 DC004186
Award Recipient
:
Monte Westerfield
Funded by: funder-id http://dx.doi.org/10.13039/100002108, Friedreich's Ataxia Research Alliance;
Award Recipient
:
Hugo J. Bellen
Confocal microscopy was supported in part by the Baylor College of Medicine IDDRC
grant number 1U54 HD083092 from the Eunice Kennedy Shriver National Institute of Child
Health & Human Development.
https://www.nichd.nih.gov. JJ was supported by National Institutes of Health GM079684
http://www.nih.gov. MTL was supported by Baylor College of Medicine Cancer Center grant P30 CA125123,
National Institutes of Health/National cancer institute grant U54 CA149196
http://www.cancer.gov and Breast Cancer SPORE P50 CA50183
http://trp.cancer.gov/spores/breast. AKG was supported by National Institutes of Health DC010987 nidcd.nih.gov. MW was
supported by National Institute of Child Health and Human Development P01 HD22486
https://www.nichd.nih. and National Institute on Deafness and Other Communication Disorders R01 DC004186
http://www.nidcd.nih.gov. HJB was supported by Howard Hughes Medical Institute
http://www.hhmi.org/scientists/hugo-j-bellen, Friedreich's Ataxia Research Alliance
http://www.curefa.org/index.php and Target ALS
http://www.targetals.org/index.html. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Cell Signaling
Subject:
Hedgehog Signaling
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Cloning
Subject:
Research and Analysis Methods
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Molecular Biology Techniques
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Cloning
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Post-Translational Modification
Subject:
Ubiquitination
Subject:
Research and Analysis Methods
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Model Organisms
Subject:
Animal Models
Subject:
Zebrafish
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Animals
Subject:
Vertebrates
Subject:
Fishes
Subject:
Osteichthyes
Subject:
Zebrafish
Subject:
Research and Analysis Methods
Subject:
Precipitation Techniques
Subject:
Immunoprecipitation
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Head
Subject:
Eyes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Head
Subject:
Eyes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Ocular System
Subject:
Eyes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Ocular System
Subject:
Eyes
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Animal Models
Subject:
Drosophila Melanogaster
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Animals
Subject:
Invertebrates
Subject:
Arthropoda
Subject:
Insects
Subject:
Drosophila
Subject:
Drosophila Melanogaster
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Gene regulation
Subject:
Small interfering RNAs
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
Non-coding RNA
Subject:
Small interfering RNAs