Lunar reference systems represent a fundamental aspect of lunar exploration. This paper presents a review of the topic in the context of the ESA lunar programme, MoonLight. This paper describes the current state of the art in the definition of the lunar reference frame and introduces TCL, a lunar time scale based on IAU resolutions. It also proposes several possible implementations of this time scale for orbiting and ground-based clocks. Finally, it provides an assessment of the improvement of the lunar reference frame that would result from the addition of lunar retro-reflectors on the Moon surface and the use of orbiter altimetry. This document is an appendix dedicated to lunar reference system definition of a more global document dedicated to the presentation of new concepts in orbit determination and time synchronization of a lunar radio navigation system.