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      Acupuncture Therapy as an Evidence-Based Nonpharmacologic Strategy for Comprehensive Acute Pain Care: The Academic Consortium Pain Task Force White Paper Update

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          Abstract

          Background

          A crisis in pain management persists, as does the epidemic of opioid overdose deaths, addiction, and diversion. Pain medicine is meeting these challenges by returning to its origins: the Bonica model of multidisciplinary pain care. The 2018 Academic Consortium White Paper detailed the historical context and magnitude of the pain crisis and the evidence base for nonpharmacologic strategies. More than 50% of chronic opioid use begins in the acute pain care setting. Acupuncture may be able to reduce this risk.

          Objective

          This article updates the evidence base for acupuncture therapy for acute pain with a review of systematic reviews and meta-analyses on postsurgical/perioperative pain with opioid sparing and acute nonsurgical/trauma pain, including acute pain in the emergency department.

          Methods

          To update reviews cited in the 2018 White Paper, electronic searches were conducted in PubMed, MEDLINE, CINAHL, and the Cochrane Central Register of Controlled Trials for “acupuncture” and “acupuncture therapy” and “acute pain,” “surgery,” “peri-operative,” “trauma,” “emergency department,” “urgent care,” “review(s) ,” “systematic review,” “meta-analysis,” with additional manual review of titles, links, and reference lists.

          Results

          There are 22 systematic reviews, 17 with meta-analyses of acupuncture in acute pain settings, and a review for acute pain in the intensive care unit. There are additional studies of acupuncture in acute pain settings.

          Conclusion

          The majority of reviews found acupuncture therapy to be an efficacious strategy for acute pain, with potential to avoid or reduce opioid reliance. Future multicenter trials are needed to clarify the dosage and generalizability of acupuncture for acute pain in the emergency department. With an extremely low risk profile, acupuncture therapy is an important strategy in comprehensive acute pain care.

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          Most cited references131

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          Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians.

          The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on noninvasive treatment of low back pain.
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            Global, regional, and national burden of migraine and tension-type headache, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

            Summary Background Through the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use data from the GBD 2016 study to provide new estimates for prevalence and years of life lived with disability (YLDs) for migraine and tension-type headache and to present the methods and results in an accessible way for clinicians and researchers of headache disorders. Methods Data were derived from population-based cross-sectional surveys on migraine and tension-type headache. Prevalence for each sex and 5-year age group interval (ie, age 5 years to ≥95 years) at different time points from 1990 and 2016 in all countries and GBD regions were estimated using a Bayesian meta-regression model. Disease burden measured in YLDs was calculated from prevalence and average time spent with headache multiplied by disability weights (a measure of the relative severity of the disabling consequence of a disease). The burden stemming from medication overuse headache, which was included in earlier iterations of GBD as a separate cause, was subsumed as a sequela of either migraine or tension-type headache. Because no deaths were assigned to headaches as the underlying cause, YLDs equate to disability-adjusted life-years (DALYs). We also analysed results on the basis of the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility. Findings Almost three billion individuals were estimated to have a migraine or tension-type headache in 2016: 1·89 billion (95% uncertainty interval [UI] 1·71–2·10) with tension-type headache and 1·04 billion (95% UI 1·00–1·09) with migraine. However, because migraine had a much higher disability weight than tension-type headache, migraine caused 45·1 million (95% UI 29·0–62·8) and tension-type headache only 7·2 million (95% UI 4·6–10·5) YLDs globally in 2016. The headaches were most burdensome in women between ages 15 and 49 years, with migraine causing 20·3 million (95% UI 12·9–28·5) and tension-type headache 2·9 million (95% UI 1·8–4·2) YLDs in 2016, which was 11·2% of all YLDs in this age group and sex. Age-standardised DALYs for each headache type showed a small increase as SDI increased. Interpretation Although current estimates are based on limited data, our study shows that headache disorders, and migraine in particular, are important causes of disability worldwide, and deserve greater attention in health policy debates and research resource allocation. Future iterations of this study, based on sources from additional countries and with less methodological heterogeneity, should help to provide stronger evidence of the need for action. Funding Bill & Melinda Gates Foundation.
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              CDC Guideline for Prescribing Opioids for Chronic Pain--United States, 2016.

              Primary care clinicians find managing chronic pain challenging. Evidence of long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious risks, including opioid use disorder and overdose.
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                Author and article information

                Contributors
                Journal
                Pain Med
                Pain Med
                painmedicine
                Pain Medicine: The Official Journal of the American Academy of Pain Medicine
                Oxford University Press
                1526-2375
                1526-4637
                September 2022
                17 June 2022
                17 June 2022
                : 23
                : 9
                : 1582-1612
                Affiliations
                Department of Family Medicine & Community Health, Icahn School of Medicine at Mount Sinai , New York, New York
                University Hospitals, Connor Whole Health, Cleveland Medical Center , Cleveland, Ohio
                Department of Family Medicine and Community Health, Case Western Reserve University , Cleveland, Ohio
                University of Utah College of Nursing , Salt Lake City, Utah
                Department of Family Medicine, and Anesthesiology & Pain Medicine, University of Washington School of Medicine , Seattle, Washington, USA
                Author notes
                Correspondence to: Arya Nielsen, PhD, Department of Family Medicine & Community Health, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue L5-40 New York, NY 10029 212-659-1141 New York, NY, USA. E-mail: Arya.Nielsen@ 123456mountsinai.org .
                Author information
                https://orcid.org/0000-0003-3370-9123
                https://orcid.org/0000-0001-9581-0564
                Article
                pnac056
                10.1093/pm/pnac056
                9434305
                35380733
                02403e93-709f-4669-b3a1-26f2529396e8
                © The Author(s) 2022. Published by Oxford University Press on behalf of the American Academy of Pain Medicine.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 15 October 2021
                : 16 March 2022
                : 23 March 2022
                Page count
                Pages: 31
                Funding
                Funded by: Academic Consortium for Integrative Medicine & Health, Pain Task Force Project;
                Funded by: National Center of Complementary and Integrative Health;
                Funded by: NCCIH, DOI 10.13039/100008460;
                Funded by: National Institutes of Health, DOI 10.13039/100000002;
                Award ID: R01AT010598
                Funded by: National Institutes of Health, DOI 10.13039/100000002;
                Categories
                Integrative Medicine Section
                Review Article
                AcademicSubjects/MED00010

                Anesthesiology & Pain management
                Anesthesiology & Pain management

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