Effects of loading on chondrocyte hypoxia, HIF-1α and VEGF in the mandibular condylar cartilage of young rats.

Yu, J.; Liang, F.; Huang, H.; Pirttiniemi, P; Yu, D.

doi:10.1111/ocr.12212

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Effects of loading on chondrocyte hypoxia, HIF-1α and VEGF in the mandibular condylar cartilage of young rats.

Author(s): J Yu ¹ , F Liang ² , H Huang ² , P Pirttiniemi ¹ , D Yu ³

Publication date (Electronic): Feb 2018

Journal: Orthodontics & craniofacial research

Publisher: Wiley

Keywords: condylar cartilage, hypoxia, hypoxia-inducible factor 1-alpha (HIF-1α), loading, vascular endothelial growth factor (VEGF)

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Abstract

To investigate hypoxia-inducible factor 1-alpha (HIF-1α) and vascular endothelial growth factor (VEGF) expression under altered loading, and to explore the relationship between loading and hypoxia in the mandibular condylar cartilage of young rats.

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Journal ID (iso-abbrev): Orthod Craniofac Res

Title: Orthodontics & craniofacial research

Publisher: Wiley

ISSN (Electronic): 1601-6343

ISSN (Print): 1601-6335

Publication date (Electronic): Feb 2018

Volume: 21

Issue: 1

Affiliations

[1 ] Department of Oral Development and Orthodontics, Institute of Dentistry, University of Oulu, Oulu, Finland.

[2 ] Department of Oral and Maxillofacial Surgery, College of Stomatology, Guangxi Medical University, Nanning, China.

[3 ] Department of Stomatology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.

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DOI: 10.1111/ocr.12212

PubMed ID: 29271061

SO-VID: 022c12f5-9c17-44c0-920a-5c7a387515bf

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Keywords: hypoxia,condylar cartilage,loading,vascular endothelial growth factor (VEGF),hypoxia-inducible factor 1-alpha (HIF-1α)

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Keywords: hypoxia, condylar cartilage, loading, vascular endothelial growth factor (VEGF), hypoxia-inducible factor 1-alpha (HIF-1α)

Effects of loading on chondrocyte hypoxia, HIF-1α and VEGF in the mandibular condylar cartilage of young rats.

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