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      Traditional medicine in Incahuasi: An ethnobotanical study

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          Abstract

          Introduction: Understanding the use of medicinal plants as herbal medicines is considered essential for the survival and continuity of humanity. Since ancient times, the origin and development of natural and traditional medicine have been intrinsically linked to humanity struggle for survival. Nowadays, ethnobotanical studies are employed as a tool for the preservation and conservation not only of taxonomic biodiversity but also of cultural biodiversity.

          Methodology: A descriptive research with a quantitative, non-experimental cross-sectional design was carried out. The study was conducted in six Quechua-speaking communities in the district of Incahuasi (3,000 meters above sea level), selected for convenience considering factors such as altitude, accessibility, and proximity to the city. A questionnaire was administered to 32 residents from the communities, who shared their knowledge about medicinal plants, providing relevant information about them. The gender of the participants was considered because men and women use traditional medicine and the knowledge of them is transmitted from parents to children.

          Results: During the study, a total of 46 medicinal species were recorded, belonging to 42 genera and 22 botanical families. The most representative medicinal families used by the informants of the communities were Asteraceae (30.4%) and Lamiaceae (15.2%). It is also worth mentioning the genera Salvia and Baccharis, with 3 and 2 species respectively, which are commonly used to treat various ailments and diseases.

          Conclusions: Ethnobotanical information was collected on the medicinal plants used by the community members of the selected communities in Incahuasi, and the corresponding data were recorded. A total of 46 plants were collected, with the majority belonging to the Asteraceae and Lamiaceae families.

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          Most cited references42

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          The transcription factor, nuclear factor erythroid 2 p45-related factor 2 (Nrf2), acts as a sensor of oxidative or electrophilic stresses and plays a pivotal role in redox homeostasis. Oxidative or electrophilic agents cause a conformational change in the Nrf2 inhibitory protein Keap1 inducing the nuclear translocation of the transcription factor which, through its binding to the antioxidant/electrophilic response element (ARE/EpRE), regulates the expression of antioxidant and detoxifying genes such as heme oxygenase 1 (HO-1). Nrf2 and HO-1 are frequently upregulated in different types of tumours and correlate with tumour progression, aggressiveness, resistance to therapy, and poor prognosis. This review focuses on the Nrf2/HO-1 stress response mechanism as a promising target for anticancer treatment which is able to overcome resistance to therapies.
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            Estrategia de la OMS sobre medicina tradicional 2014-2023

            (2013)
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              Comparative phylogenetic methods and the cultural evolution of medicinal plant use

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                Author and article information

                Contributors
                Role: ConceptualizationRole: Data CurationRole: Formal AnalysisRole: InvestigationRole: MethodologyRole: Project AdministrationRole: SupervisionRole: ValidationRole: Writing – Original Draft PreparationRole: Writing – Review & Editing
                Role: Data CurationRole: InvestigationRole: MethodologyRole: Writing – Original Draft PreparationRole: Writing – Review & Editing
                Role: ConceptualizationRole: Funding AcquisitionRole: Writing – Review & Editing
                Role: Data CurationRole: Formal AnalysisRole: MethodologyRole: Writing – Original Draft PreparationRole: Writing – Review & Editing
                Role: Formal AnalysisRole: MethodologyRole: Writing – Original Draft PreparationRole: Writing – Review & Editing
                Role: Formal AnalysisRole: MethodologyRole: Writing – Review & Editing
                Role: Data CurationRole: MethodologyRole: Writing – Original Draft PreparationRole: Writing – Review & Editing
                Role: Formal AnalysisRole: MethodologyRole: Writing – Review & Editing
                Journal
                F1000Res
                F1000Res
                F1000Research
                F1000 Research Limited (London, UK )
                2046-1402
                31 August 2023
                2023
                : 12
                : 1075
                Affiliations
                [1 ]Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, 14012, Peru
                [2 ]Escuela de Medicina Humana, Universidad Señor de Sipán, Chiclayo, 14012, Peru
                [1 ]Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo, Trujillo, Peru
                [1 ]Departamento académico de botánica. Facultad de Ciencias Biológicas, National University of the Peruvian Amazon, Iquitos, Loreto, Peru
                [1 ]Universidad Tecnica de Manabi, Portoviejo, Manabí Province, Ecuador
                Author notes

                No competing interests were disclosed.

                Competing interests: No competing interests were disclosed.

                Competing interests: No competing interests were disclosed.

                Competing interests: No competing interests were disclosed.

                Author information
                https://orcid.org/0000-0003-0012-1817
                https://orcid.org/0000-0001-7267-0204
                https://orcid.org/0000-0001-7940-7580
                Article
                10.12688/f1000research.138398.1
                10993006
                38577227
                00a90120-53cd-474b-9879-05780b126ce9
                Copyright: © 2023 Morales Ramos JG et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 14 August 2023
                Funding
                Funded by: Universidad De San Martín de Porres - FN
                This work was supported by Universidad De San Martín de Porres - FN (Letter No. 141 - 2021 - CIEI-FMH-USMP).
                The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Articles

                traditional medicine,ethnobotany,systematic botany,medicinal plants

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