For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
17
views
124
references
 Top references
cited by
9
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      102
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: not found

      Focal ablation therapy for renal cancer in the era of active surveillance and minimally invasive partial nephrectomy

      Author(s): , ,
      Publication date Created:
      Publication date (Print):
      Journal: Nature Reviews Urology
      Publisher: Springer Nature

      Read this article at

      ScienceOpenPublisher
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Ginzburg et al. review the evolving role of focal ablative therapies in the management of small renal masses. They describe the techniques, the role of image guidance, pretreatment biopsy, and post-treatment surveillance, as well as data on safety, oncological, and functional outcomes.

          Related collections

          Most cited references124

          • Record: found
          • Abstract: not found
          • Article: not found

          Guideline for management of the clinical T1 renal mass.

          Steven Campbell, Andrew Novick, Arie S. Belldegrun … (2009)
          Article 0 comments Cited 265 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Renal cell cancer stage migration: analysis of the National Cancer Data Base.

            Christopher Kane, Katherine Mallin, Jamie Ritchey … (2008)
            Evidence exists to suggest a pattern of increasing early diagnosis of renal cell carcinoma (RCC). The aim of the study was to analyze patterns of disease presentation and outcome of RCC by AJCC stage using data from the National Cancer Data Base (NCDB) over a 12-year period. The NCDB was queried for adults diagnosed between 1993 and 2004 presenting with ICD-O-2 of 3 renal cell tumors arising in the kidney. Cases were classified by demographics, 2002 AJCC stage (6th edition), and histology. The Cochran-Armitage Test for Trend was used to determine statistical significance of trends over time. Cox regression multivariate analysis was used to evaluate the impact of stage and histology on relative survival. SPSS 14.0 was used for analyses. Between 1993 and 2004 a total of 205,963 patients from the NCDB fit our case definition of RCC. Comparisons between 1993 and 2004 data show an increase in stage I disease and decrease in stage II, III, and IV disease (P < or = .001). The size of stage I tumors also decreased from a mean of 4.1 cm in 1993 to 3.6 cm in 2003. In multivariate analysis, stage, but not histology, predicted relative survival. A 3.3% increase in survival was found for patients diagnosed in 1998 compared with patients diagnosed in 1993. A greater proportion of newly diagnosed patients with RCC currently present with stage I disease compared with earlier years. Stage predicts relative survival for patients with kidney cancer. More recently diagnosed patients have improved relative survival. (Copyright) 2008 American Cancer Society.
            Article 0 comments Cited 124 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Irreversible electroporation for nonthermal tumor ablation in the clinical setting: a systematic review of safety and efficacy.

              Jack van Loon, J Vieveen, Karin Nielsen … (2014)
              To provide an overview of current clinical results of irreversible electroporation (IRE), a novel, nonthermal tumor ablation technique that uses electric pulses to induce cell death, while preserving structural integrity of bile ducts and vessels. All in-human literature on IRE reporting safety or efficacy or both was included. All adverse events were recorded. Tumor response on follow-up imaging from 3 months onward was evaluated. In 16 studies, 221 patients had 325 tumors treated in liver (n = 129), pancreas (n = 69), kidney (n = 14), lung (n = 6), lesser pelvis (n = 1), and lymph node (n = 2). No major adverse events during IRE were reported. IRE caused only minor complications in the liver; however, three major complications were reported in the pancreas (bile leak [n = 2], portal vein thrombosis [n = 1]). Complete response at 3 months was 67%-100% for hepatic tumors (93%-100% for tumors o 3 cm). Pancreatic IRE combined with surgery led to prolonged survival compared with control patients (20 mo vs 13 mo) and significant pain reduction. In cases where other techniques are unsuitable, IRE is a promising modality for the ablation of tumors near bile ducts and blood vessels. This articles gives an extensive overview of the available evidence, which is limited in terms of quality and quantity. With the limitations of the evidence in mind, IRE of central liver tumors seems relatively safe without major complications, whereas complications after pancreatic IRE appear more severe. The available limited results for tumor control are generally good. Overall, the future of IRE for difficult-to-reach tumors appears promising. Copyright © 2014 SIR. Published by Elsevier Inc. All rights reserved.
              Article 0 comments Cited 114 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Title: Nature Reviews Urology
                Abbreviated Title: Nat Rev Urol
                Publisher: Springer Nature
                ISSN (Print): 1759-4812
                ISSN (Electronic): 1759-4820
                Publication date Created: September 12 2017
                Publication date (Print): September 12 2017
                Volume:
                Issue:
                Article
                DOI: 10.1038/nrurol.2017.143
                SO-VID: c2cee609-8068-4d8f-8f23-6c050ca1ff59
                Copyright © © 2017
                History

                Data availability:

                Comments

                Comment on this article

                scite_

                Similar content102

                See all similar

                Cited by9

                See all cited by

                Most referenced authors1,243

                See all reference authors