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      Cancer of the gastroesophageal junction: a diagnosis, classification, and management review.

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          Abstract

          Management of gastroesophageal junction (GEJ) adenocarcinoma is a controversial topic. The rising incidence of this cancer requires a clear consensus to ensure proper management. Application of oncological principles for tumors of the esophagus or stomach is not possible because of comparative differences in the biology of GEJ adenocarcinoma, leading to different therapeutic options. Staging work-up with endoscopy, endosonography, and PET is essential to inform the choice of neoadjuvant treatment and surgical approach to GEJ adenocarcinoma. Surgery remains the only curative treatment and should be undertaken in specialized centers.

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          Author and article information

          Journal
          Ann N Y Acad Sci
          Annals of the New York Academy of Sciences
          Wiley
          1749-6632
          0077-8923
          December 2018
          : 1434
          : 1
          Affiliations
          [1 ] Visceral Surgery Department, Geneva University Hospital, Genève, Switzerland.
          [2 ] Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany.
          [3 ] Department of Surgical Gastroenterology and Center of Excellence for Upper Gastro Intestinal Surgery, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, India.
          [4 ] Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany.
          [5 ] Department of Surgery, Paracelsus Medical University, Salzburg, Austria.
          [6 ] Department of General Surgery, University of Verona, Verona, Italy.
          [7 ] Department of Surgery, Royal Marsden Hospital, London, UK.
          Article
          10.1111/nyas.13954
          30138540
          4cfe8679-1076-48d0-ad82-0fb8b9bbbd63
          © 2018 New York Academy of Sciences.
          History

          FLOT,esophagectomy,minimally invasive
          FLOT, esophagectomy, minimally invasive

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