Axillary Ultrasound After Neoadjuvant Chemotherapy and Its Impact on Sentinel Lymph Node Surgery: Results From the American College of Surgeons Oncology Group Z1071 Trial (Alliance).

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Abstract

The American College of Surgeons Oncology Group Z1071 trial reported a 12.6% false-negative rate (FNR) for sentinel lymph node (SLN) surgery after neoadjuvant chemotherapy (NAC) in cN1 disease. Patients were not selected for surgery based on response, but a secondary end point was to determine whether axillary ultrasound (AUS) after NAC after fine-needle aspiration cytology can identify abnormal nodes and guide patient selection for SLN surgery.

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Journal

Journal ID (iso-abbrev): J. Clin. Oncol.

Title: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

ISSN (Electronic): 1527-7755

ISSN (Print): 0732-183X

Publication date (Electronic): Oct 20 2015

Volume: 33

Issue: 30

Affiliations

[1 ] Judy C. Boughey, Mayo Clinic; Karla V. Ballman, Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN; Kelly K. Hunt, Elizabeth A. Mittendorf, and Huong T. Le-Petross, The University of Texas MD Anderson Cancer Center, Houston, TX; Linda M. McCall, Alliance Statistics and Data Center, Duke University, Durham, NC; Gretchen M. Ahrendt, University of Pittsburgh Cancer Institute, Pittsburgh, PA; and Lee G. Wilke, University of Wisconsin Hospital and Clinics, Madison, WI. boughey.judy@mayo.edu.

[2 ] Judy C. Boughey, Mayo Clinic; Karla V. Ballman, Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN; Kelly K. Hunt, Elizabeth A. Mittendorf, and Huong T. Le-Petross, The University of Texas MD Anderson Cancer Center, Houston, TX; Linda M. McCall, Alliance Statistics and Data Center, Duke University, Durham, NC; Gretchen M. Ahrendt, University of Pittsburgh Cancer Institute, Pittsburgh, PA; and Lee G. Wilke, University of Wisconsin Hospital and Clinics, Madison, WI.

Article

Publisher Item ID: JCO.2014.57.8401

DOI: 10.1200/JCO.2014.57.8401

PubMed ID: 25646192

SO-VID: 95fc3e64-d76d-4396-91f3-66aef1d29aec

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