Aggressive treatment of acute kidney injury and hyperkalemia improves survival in a combat relevant trauma model in swine.

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Abstract

Our swine model of pulmonary contusion (PC) and hemorrhagic shock (HS) was initially complicated by renal failure, hyperkalemia, and premature death. To study the effects of novel therapies on organ failure, improved survival was necessary requiring the design of an aggressive treatment regimen.

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Author and article information

Journal

Journal ID (iso-abbrev): Am J Surg

Title: American journal of surgery

Publisher: Elsevier BV

ISSN (Electronic): 1879-1883

ISSN (Print): 0002-9610

Publication date (Electronic): May 2020

Volume: 219

Issue: 5

Affiliations

[1 ] Oregon Health & Science University, Portland, OR, USA. Electronic address: smithsaw@ohsu.edu.

[2 ] Oregon Health & Science University, Portland, OR, USA.

[3 ] University of California San Francisco, San Francisco, CA, USA.

Article

Publisher Item ID: S0002-9610(20)30141-0

DOI: 10.1016/j.amjsurg.2020.02.058

PubMed ID: 32245610

SO-VID: 4c88888a-f05d-48b6-adb9-797b7d996e35

History

Keywords: Hyperkalemia,Trauma,Swine model

Data availability:

Keywords: Hyperkalemia, Trauma, Swine model

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