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      Bone quality in endocrine diseases: determinants and clinical relevance.

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          Abstract

          Bone is one of the main targets of hormones and endocrine diseases are frequent causes of secondary osteoporosis and fractures in real-world clinical practice. However, diagnosis of skeletal fragility and prediction of fractures in this setting could be a challenge, since the skeletal alterations induced by endocrine disorders are not generally captured by dual-energy X-ray absorptiometry (DXA) measurement of bone mineral density (BMD), that is the gold standard for diagnosis of osteoporosis in the general population. The aim of this paper is to review the existing evidence related to bone quality features in endocrine diseases, proposing assessment with new techniques in the future.

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          Radiomics: Images Are More than Pictures, They Are Data

          Robert Gillies, Paul E Kinahan, Hedvig Hricak (2015)
          This report describes the process of radiomics, its challenges, and its potential power to facilitate better clinical decision making, particularly in the care of patients with cancer.
          Article 0 comments Cited 2104 times – based on 0 reviews     Review now
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            Radiomics: the bridge between medical imaging and personalized medicine

            Seán Froudist Walsh, Joachim Wildberger, Felix Mottaghy … (2017)
            Radiomics, the high-throughput mining of quantitative image features from standard-of-care medical imaging that enables data to be extracted and applied within clinical-decision support systems to improve diagnostic, prognostic, and predictive accuracy, is gaining importance in cancer research. Radiomic analysis exploits sophisticated image analysis tools and the rapid development and validation of medical imaging data that uses image-based signatures for precision diagnosis and treatment, providing a powerful tool in modern medicine. Herein, we describe the process of radiomics, its pitfalls, challenges, opportunities, and its capacity to improve clinical decision making, emphasizing the utility for patients with cancer. Currently, the field of radiomics lacks standardized evaluation of both the scientific integrity and the clinical relevance of the numerous published radiomics investigations resulting from the rapid growth of this area. Rigorous evaluation criteria and reporting guidelines need to be established in order for radiomics to mature as a discipline. Herein, we provide guidance for investigations to meet this urgent need in the field of radiomics.
            Article 0 comments Cited 1544 times – based on 0 reviews     Review now
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              Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline

              Shalender Bhasin, Juan Brito, Glenn Cunningham … (2018)
              To update the "Testosterone Therapy in Men With Androgen Deficiency Syndromes" guideline published in 2010.
              Article 0 comments Cited 341 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (iso-abbrev): J Endocrinol Invest
                Title: Journal of endocrinological investigation
                Publisher: Springer Science and Business Media LLC
                ISSN (Electronic): 1720-8386
                ISSN (Print): 0391-4097
                Publication date (Electronic): Jul 2023
                Volume: 46
                Issue: 7
                Affiliations
                [1 ] Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Viale GB Morgagni 50, 50134, Florence, Italy.
                [2 ] Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00161, Rome, Italy.
                [3 ] Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
                [4 ] Endocrinology and Diabetology Service, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
                [5 ] Endocrinology Unit, Medical Department, Azienda Usl, Maggiore-Bellaria Hospital, Bologna, Italy.
                [6 ] Unit of Endocrinology and Diabetes, Department of Medicine, University Campus Bio-Medico di Roma, 00128, Rome, Italy.
                [7 ] Department of Movement, Human and Health Sciences, Health Sciences Section, University "Foro Italico", Rome, Italy.
                [8 ] Department of Biomedical Sciences, Humanitas University, Via R. Levi Montalcini 4, 20090, Pieve Emanuele, MI, Italy.
                [9 ] Endocrinology, Diabetology and Andrology Unit, IRCCS Humanitas Research Hospital, Via A Manzoni 56, 20089, Rozzano, MI, Italy.
                [10 ] Radiology Unit, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
                [11 ] University of Milan, Department of Biomedical Sciences for Health, Milan, Italy.
                [12 ] Division of Bone and Mineral Diseases, Washington University in St Louis, St Louis, MO, USA.
                [13 ] Department of Biomedical Sciences, Humanitas University, Via R. Levi Montalcini 4, 20090, Pieve Emanuele, MI, Italy. gherardo.mazziotti@hunimed.eu.
                [14 ] Endocrinology, Diabetology and Andrology Unit, IRCCS Humanitas Research Hospital, Via A Manzoni 56, 20089, Rozzano, MI, Italy. gherardo.mazziotti@hunimed.eu.
                Article
                Publisher Item ID: 10.1007/s40618-023-02056-w
                DOI: 10.1007/s40618-023-02056-w
                PubMed ID: 36918505
                SO-VID: 6a42718d-27a0-4ed5-a950-a8f1df6615e8
                History

                Keywords: Hyperparathyroidism,Hormones,Hyperthyroidism,Hypogonadism,TBS REMS,Acromegaly,Bone quality,Bone structure,Growth hormone deficiency,Diabetes,Cushing syndrome
                Data availability:
                Keywords: Hyperparathyroidism, Hormones, Hyperthyroidism, Hypogonadism, TBS REMS, Acromegaly, Bone quality, Bone structure, Growth hormone deficiency, Diabetes, Cushing syndrome

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