Contributors
Xiaoxi Yang: Role: InvestigationRole: MethodologyRole: Writing – original draft
Zhongqiang Chen: Role: ConceptualizationRole: Supervision
Xiangyu Meng: Role: Methodology
Chuiguo Sun: Role: Methodology
Mengtao Li: Role: Methodology
Li Shu: Role: Methodology
Dongwei Fan: Role: Methodology
Tianqi Fan: Role: Methodology
Ann Y. Huang: Role: Methodology
Chi Zhang:
ORCID: http://orcid.org/0000-0002-7821-483X
Role: ConceptualizationRole: SupervisionRole: Writing – review & editing
Xing-Ming Shi: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
17
December
2018
Publication date Collection: 2018
Volume: 13
Issue: 12
Electronic Location Identifier: e0209300
Affiliations
[1
]
Department of Orthopedics, Peking University Third Hospital, Beijing, China
[2
]
Central Laboratory, Peking University International Hospital, Beijing, China
[3
]
Daobio, Inc. Dallas, Texas, United States of America
[4
]
Department of Orthopedics, Peking University International Hospital, Beijing, China
[5
]
Bone Research Laboratory, University of Texas Southwestern Medical Center, Dallas,
Texas, United States of America
Augusta University, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-18-31944
DOI: 10.1371/journal.pone.0209300
PMC ID: 6296551
PubMed ID: 30557327
SO-VID: 2c0d4eae-6693-47f0-ad50-f9b8b25f88e7
Copyright © © 2018 Yang et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 6
November
2018
Date
accepted
: 3
December
2018
Page count
Figures: 4,
Tables: 0,
Pages: 11
Funding
This work was supported by the National Natural Science Foundation of China (ZC, Grant
numbers: 81772381 and 81700779) and Beijing Municipal Science&Technology Commission
(CZ, Grant number: Z181100001818006). The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Bone Remodeling
Subject:
Ossification
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Physiological Processes
Subject:
Bone Remodeling
Subject:
Ossification
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Cell Signaling
Subject:
Notch Signaling
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Cell Differentiation
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Cardiovascular Physiology
Subject:
Angiogenesis
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Cardiovascular Physiology
Subject:
Angiogenesis
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Angiogenesis
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Gene regulation
Subject:
Small interfering RNAs
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
Non-coding RNA
Subject:
Small interfering RNAs
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Cell Differentiation
Subject:
Osteoblast Differentiation
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
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