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      Global status, recent trends, and knowledge mapping of olive oil research and cardiovascular disease: 50 years of investigations through bibliometric analysis

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          Abstract

          In the Mediterranean diet, olive oil serves as the predominant fat source and has been linked to a decreased risk of mortality related to cardiovascular diseases (CVD). Still, there is no conclusive evidence correlating olive oil consumption to CVD. The aim of this study is to assess the global research, current research trends, and knowledge mapping related to the correlation between the consumption of olive oil and CVD using bibliometric analysis. On August 19, 2023, a title‐specific literature search was conducted on the Scopus database using the search terms “olive oil” and “cardiovascular disease” with a date range of the past 50 years. Subsequently, bibliometric tools such as VOSviewer and Bibliometrix were employed to analyze and evaluate the obtained documents. The search yielded ( n = 429) publications and showed an upward trend in the annual publication count over the last five decades. The publication number exhibited a gradual increase with a rate of 5.55%. The results also indicated that 2530 authors, 759 institutions, 47 countries, and 223 journals have publications in this research domain. The present bibliometric study will be a valuable research reference for describing the worldwide research patterns concerning the relationship between olive oil and CVD during the past 50 years. In the future, the application of olive oil for the treatment of CVDs may be an emerging research trend. Apart from this, collaborations among authors, countries, and organizations are expected.

          Abstract

          The present bibliometric study will be a valuable research reference for describing the worldwide research patterns concerning the relationship between olive oil and CVD during the past 50 years.

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          How to conduct a bibliometric analysis: An overview and guidelines

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            Adherence to a Mediterranean diet and survival in a Greek population.

            Adherence to a Mediterranean diet may improve longevity, but relevant data are limited. We conducted a population-based, prospective investigation involving 22,043 adults in Greece who completed an extensive, validated, food-frequency questionnaire at base line. Adherence to the traditional Mediterranean diet was assessed by a 10-point Mediterranean-diet scale that incorporated the salient characteristics of this diet (range of scores, 0 to 9, with higher scores indicating greater adherence). We used proportional-hazards regression to assess the relation between adherence to the Mediterranean diet and total mortality, as well as mortality due to coronary heart disease and mortality due to cancer, with adjustment for age, sex, body-mass index, physical-activity level, and other potential confounders. During a median of 44 months of follow-up, there were 275 deaths. A higher degree of adherence to the Mediterranean diet was associated with a reduction in total mortality (adjusted hazard ratio for death associated with a two-point increment in the Mediterranean-diet score, 0.75 [95 percent confidence interval, 0.64 to 0.87]). An inverse association with greater adherence to this diet was evident for both death due to coronary heart disease (adjusted hazard ratio, 0.67 [95 percent confidence interval, 0.47 to 0.94]) and death due to cancer (adjusted hazard ratio, 0.76 [95 percent confidence interval, 0.59 to 0.98]). Associations between individual food groups contributing to the Mediterranean-diet score and total mortality were generally not significant. Greater adherence to the traditional Mediterranean diet is associated with a significant reduction in total mortality. Copyright 2003 Massachusetts Medical Society
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              Monounsaturated fatty acids, olive oil and health status: a systematic review and meta-analysis of cohort studies

              Background The aim of the present meta-analysis of cohort studies was to focus on monounsaturated fat (MUFA) and cardiovascular disease, cardiovascular mortality as well as all-cause mortality, and to distinguish between the different dietary sources of MUFA. Methods Literature search was performed using the electronic databases PUBMED, and EMBASE until June 2nd, 2014. Study specific risk ratios and hazard ratios were pooled using a inverse variance random effect model. Results Thirty-two cohort studies (42 reports) including 841,211 subjects met the objectives and were included. The comparison of the top versus bottom third of the distribution of a combination of MUFA (of both plant and animal origin), olive oil, oleic acid, and MUFA:SFA ratio in each study resulted in a significant risk reduction for: all-cause mortality (RR: 0.89, 95% CI 0.83, 0.96, p = 0.001; I2 = 64%), cardiovascular mortality (RR: 0.88, 95% CI 0.80, 0.96, p = 0.004; I2 = 50%), cardiovascular events (RR: 0.91, 95% CI 0.86, 0.96, p = 0.001; I2 = 58%), and stroke (RR: 0.83, 95% CI 0.71, 0.97, p = 0.02; I2 = 70%). Following subgroup analyses, significant associations could only be found between higher intakes of olive oil and reduced risk of all-cause mortality, cardiovascular events, and stroke, respectively. The MUFA subgroup analyses did not reveal any significant risk reduction. Conclusion The results indicate an overall risk reduction of all-cause mortality (11%), cardiovascular mortality (12%), cardiovascular events (9%), and stroke (17%) when comparing the top versus bottom third of MUFA, olive oil, oleic acid, and MUFA:SFA ratio. MUFA of mixed animal and vegetable sources per se did not yield any significant effects on these outcome parameters. However, only olive oil seems to be associated with reduced risk. Further research is necessary to evaluate specific sources of MUFA (i.e. plant vs. animal) and cardiovascular risk. Electronic supplementary material The online version of this article (doi:10.1186/1476-511X-13-154) contains supplementary material, which is available to authorized users.
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                Author and article information

                Contributors
                semwal.prabhakar@gmail.com
                anees.khalil@dnsc.uol.edu.pk
                polrat.wil@mahidol.ac.th
                Journal
                Food Sci Nutr
                Food Sci Nutr
                10.1002/(ISSN)2048-7177
                FSN3
                Food Science & Nutrition
                John Wiley and Sons Inc. (Hoboken )
                2048-7177
                29 November 2023
                March 2024
                : 12
                : 3 ( doiID: 10.1002/fsn3.v12.3 )
                : 1465-1478
                Affiliations
                [ 1 ] Department of Biotechnology Graphic Era (Deemed to be University) Dehradun India
                [ 2 ] Natural Products Research Laboratory Uttarakhand Council for Biotechnology (UCB) Dehradun India
                [ 3 ] Research and Development Cell Graphic Era Hill University Dehradun India
                [ 4 ] Department of Biotechnology Engineering, University Institute of Engineering Chandigarh University Chandigarh India
                [ 5 ] Department of Chemistry University of Swabi Swabi Pakistan
                [ 6 ] Faculty of Allied Health Sciences, University Institute of Diet and Nutritional Sciences The University of Lahore Lahore Pakistan
                [ 7 ] Department of Medical Laboratory Technology, College of Applied Medical Sciences Taibah University Medina Saudi Arabia
                [ 8 ] Department of Clinical Tropical Medicine, Faculty of Tropical Medicine Mahidol University Bangkok Thailand
                Author notes
                [*] [* ] Correspondence

                Anees Ahmed Khalil, University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54000, Pakistan.

                Email: anees.khalil@ 123456dnsc.uol.edu.pk

                Prabhakar Semwal, Department of Biotechnology, Graphic Era (Deemed to be University), 566/6 Bell Road, Clement Town, Dehradun, Uttarakhand 248002, India.

                Email: semwal.prabhakar@ 123456gmail.com

                Polrat Wilairatana, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

                Email: polrat.wil@ 123456mahidol.ac.th

                Author information
                https://orcid.org/0000-0003-3662-0933
                Article
                FSN33885 FSN3-2023-09-2066.R1
                10.1002/fsn3.3885
                10916624
                38455210
                165a9746-5dd5-4857-8f18-8977bdf5f366
                © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 15 November 2023
                : 27 September 2023
                : 18 November 2023
                Page count
                Figures: 10, Tables: 7, Pages: 14, Words: 6306
                Categories
                Review
                Reviews
                Custom metadata
                2.0
                March 2024
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.9 mode:remove_FC converted:06.03.2024

                bibliometric analysis,cardiovascular diseases,olive oil,research trends,scopus

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