[1
]
Department of Cardiovascular Sciences, University of Leicester, Leicester, United
Kingdom; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital,
Leicester, United Kingdom.
[2
]
Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany; DZHK (German
Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, Lübeck,
Germany; University Heart Center Luebeck, Lübeck, Germany.
[3
]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry,
Queen Mary University of London, London, United Kingdom; Department of Haematology,
University of Cambridge, Cambridge, United Kingdom.
[4
]
Cardiovascular Division, Department of Medicine, Washington University School of Medicine,
Saint Louis, Missouri; Department of Genetics, Washington University School of Medicine,
Saint Louis, Missouri; McDonnell Genome Institute, Washington University School of
Medicine, Saint Louis, Missouri.
[5
]
Deutsches Herzzentrum München, Technische Universität München, München, Germany; DZHK,
Partner Site Munich Heart Alliance, Munich, Germany.
[6
]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry,
Queen Mary University of London, London, United Kingdom.
[7
]
DZHK (German Research Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel,
Lübeck, Germany; Institut für Medizinische Biometrie und Statistik, Universität zu
Lübeck, Lübeck, Germany.
[8
]
Center for Population Studies, National Heart, Lung, and Blood Institute, The Framingham
Heart Study, Framingham, Massachusetts.
[9
]
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University,
Sweden; Department of Medical Biochemistry and Biophysics, Vascular Biology Unit,
Karolinska Institutet, Stockholm, Sweden.
[10
]
Department of Physiology, Institute of Biomedicine and Translation Medicine, University
of Tartu, Tartu, Estonia; Department of Cardiac Surgery, Tartu University Hospital,
Tartu, Estonia; Clinical Gene Networks AB, Stockholm, Sweden.
[11
]
Clinical Gene Networks AB, Stockholm, Sweden; Department of Genetics & Genomic Sciences,
Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai,
New York, New York.
[12
]
Department of Genetics & Genomic Sciences, Institute of Genomics and Multiscale Biology,
Icahn School of Medicine at Mount Sinai, New York, New York.
[13
]
Department of Medical Biochemistry and Biophysics, Vascular Biology Unit, Karolinska
Institutet, Stockholm, Sweden; Department of Physiology, Institute of Biomedicine
and Translation Medicine, University of Tartu, Tartu, Estonia; Clinical Gene Networks
AB, Stockholm, Sweden; Department of Genetics & Genomic Sciences, Institute of Genomics
and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York.
[14
]
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee;
Laboratory for Molecular Cardiology, Department of Cardiology, Copenhagen University
Hospital Rigshospitalet, Copenhagen, Denmark.
[15
]
School of Public Heath, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin.
[16
]
Fred Hutchinson Cancer Research Center, Seattle, Washington; The Charles Bronfman
Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai,
New York, New York.
[17
]
The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine
at Mount Sinai, New York, New York; The Genetics of Obesity and Related Metabolic
Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York.
[18
]
Department of Internal Medicine, Division of Cardiovascular Medicine, University of
Michigan, Ann Arbor, Michigan.
[19
]
Université de Montréal, Faculté de médecine, Département de médecine, Montreal, Quebec,
Canada; Montreal Heart Institute, Montreal, Quebec, Canada.
[20
]
Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University
of Oxford, Oxford, United Kingdom; Wellcome Trust Centre for Human Genetics, University
of Oxford, Oxford, United Kingdom.
[21
]
Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts;
Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts;
Department of Medicine, Harvard Medical School, Boston, Massachusetts; Program in
Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.
[22
]
Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts;
Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts;
Department of Medicine, Harvard Medical School, Boston, Massachusetts; Program in
Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; Samsung
Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Samsung
Medical Center, Seoul, South Korea.
[23
]
The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of
Medicine at Mount Sinai, New York, New York; The Center for Statistical Genetics,
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai,
New York, New York; The Icahn Institute for Genomics and Multiscale Biology, Department
of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York,
New York; The Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of
Medicine at Mount Sinai, New York, New York.
[24
]
Department of Biostatistics, Academic Medical Center, Amsterdam, the Netherlands.
[25
]
Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover,
Hannover, Germany.
[26
]
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
[27
]
MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge,
United Kingdom.
[28
]
Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.
[29
]
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
[30
]
Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School,
Scotland, United Kingdom.
[31
]
Department of Biomedical Sciences, Humanitas University, Milan, Italy; Humanitas Clinical
and Research Center, Milan, Italy.
[32
]
Niguarda Hospital, Milan, Italy.
[33
]
Azienda Sanitaria Locale 3 San Francesco, Nuoro, Italy 3, Nuoro, Italy.
[34
]
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee;
Department of Biomedical informatics, Vanderbilt University Medical Center, Nashville,
Tennessee.
[35
]
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
[36
]
Klinik für Kardiologie, Pneumologie und Innere Medizin, Imland Klinik Rendsburg, Rendsburg,
Germany.
[37
]
Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel,
Germany.
[38
]
Institute of Human Genetics, University of Bonn, Bonn, Germany; Department of Genomics,
Life & Brain Center, University of Bonn, Bonn, Germany.
[39
]
McDonnell Genome Institute, Washington University School of Medicine, Saint Louis,
Missouri; Deutsches Herzzentrum München, Technische Universität München, München,
Germany.
[40
]
Institute of Human Genetics, University of Bonn, Bonn, Germany; Department of Genomics,
Life & Brain Center, University of Bonn, Bonn, Germany; Division of Medical Genetics,
Department of Biomedicine, University of Basel, Basel, Switzerland.
[41
]
HUNT Research Centre, Department of Public Health and General Practice, Norwegian
University of Science and Technology, Levanger, Norway; St. Olav Hospital, Trondheim
University Hospital, Trondheim, Norway.
[42
]
HUNT Research Centre, Department of Public Health and General Practice, Norwegian
University of Science and Technology, Levanger, Norway; Department of Medicine, Levanger
Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.
[43
]
Department of Public Health and Clinical Medicine, Research Unit Skellefteå, Umeå
University, Sweden.
[44
]
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital
Essen, Essen, Germany.
[45
]
Research unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research
Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II,
Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg,
Germany; German Center for Diabetes Research, Neuherberg, Germany.
[46
]
DZHK, Partner Site Munich Heart Alliance, Munich, Germany; Institute Medizinische
Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München,
Munich, Germany.
[47
]
Department of Medicine, Section of Internal Medicine, University of Verona, Verona,
Italy.
[48
]
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom;
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford,
United Kingdom; Oxford National Institute for Health Research Biomedical Research
Centre, Churchill Hospital, Old Road Headington, Oxford, Oxford, United Kingdom.
[49
]
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford,
United Kingdom.
[50
]
Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for
Environmental Health, Neuherberg, Germany.
[51
]
Estonian Genome Center, University of Tartu, Tartu, Estonia; Division of Endocrinology,
Boston Children's Hospital, Boston, Massachusetts; Department of Genetics, Harvard
Medical School, Boston, Massachusetts; Broad Institute of the Massachusetts Institute
of Technology and Harvard University, Cambridge, Massachusetts.
[52
]
Estonian Genome Center, University of Tartu, Tartu, Estonia.
[53
]
Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department
of Clinical Sciences, Lund University, Malmö, Sweden.
[54
]
Estonian Genome Center, University of Tartu, Tartu, Estonia; Institute of Molecular
and Cell Biology, Tartu, Estonia.
[55
]
School of Molecular, Genetic and Population Health Sciences, University of Edinburgh,
Medical School, Teviot Place, Edinburgh, Scotland, United Kingdom.
[56
]
National Institute for Health and Welfare (THL), Helsinki, Finland.
[57
]
Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute,
Ottawa, Ontario, Canada.
[58
]
Montreal Heart Institute, Montreal, Quebec, Canada.
[59
]
Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders
(PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
[60
]
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom;
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford,
United Kingdom.
[61
]
Merck Sharp & Dohme, Rahway, New Jersey.
[62
]
Department of Cardiology, Division Heart & Lungs, UMC Utrecht, the Netherlands; Durrer
Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the
Netherlands; Institute of Cardiovascular Science, Faculty of Population Health Sciences,
University College London, London, United Kingdom.
[63
]
Fred Hutchinson Cancer Research Center, Seattle, Washington.
[64
]
Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Ohio State
University, Columbus, Ohio.
[65
]
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
[66
]
DZHK, Partner Site Munich Heart Alliance, Munich, Germany; Institute of Genetic Epidemiology,
Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg,
Germany; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität,
Munich, Germany.
[67
]
Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center
for Environmental Health, Neuherberg, Germany; Institute of Medical Informatics, Biometry
and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich,
Germany.
[68
]
Research unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research
Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology II,
Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg,
Germany.
[69
]
MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary
Care, University of Cambridge, Cambridge, United Kingdom.
[70
]
Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom.
[71
]
Department of Cardiology, Leiden University Medical Center, Leiden and Interuniversity
Cardiology Institute of the Netherlands, Utrecht, the Netherlands.
[72
]
Université de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE,
Lille, France.
[73
]
Copenhagen University Hospital and Faculty of Health and Medical Sciences, University
of Copenhagen, Copenhagen, Denmark.
[74
]
Toulouse University School of Medicine, Toulouse, France.
[75
]
Department of Biostatistics and Epidemiology, Perelman School of Medicine, University
of Pennsylvania, Philadelphia, Pennsylvania; Center for Noncommunicable Diseases,
Karachi, Pakistan.
[76
]
British Heart Foundation, Glasgow Cardiovascular Research Centre, University of Glasgow,
Glasgow, United Kingdom.
[77
]
Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology,
Ludwig-Maximilians-Universität, Munich, Germany.
[78
]
Department of Epîdemiology and Public Health, University of Strasbourg, Strasbourg,
France.
[79
]
MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary
Care, University of Cambridge, Cambridge, United Kingdom; National Institute of Health
Research Blood and Transplant Research Unit in Donor Health and Genomics, University
of Cambridge, Cambridge, United Kingdom.
[80
]
MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary
Care, University of Cambridge, Cambridge, United Kingdom; National Institute of Health
Research Blood and Transplant Research Unit in Donor Health and Genomics, University
of Cambridge, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Hinxton,
Cambridge, United Kingdom.
[81
]
Parma University Hospital, Parma, Italy.
[82
]
The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine
at Mount Sinai, New York, New York.
[83
]
Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department
of Clinical Sciences, Lund University, Malmö, Sweden; Department of Nutrition, Harvard
School of Public Health, Boston, Massachusetts; Department of Public Health & Clinical
Medicine, Umeå University Hospital, Umeå, Sweden.
[84
]
Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds,
United Kingdom.
[85
]
Deutsches Herzzentrum München, Technische Universität München, München, Germany.
[86
]
Institute of Epidemiology and Biobank popgen, Christian-Albrechts-University Kiel,
Kiel, Germany.
[87
]
DZHK, Partner Site Munich Heart Alliance, Munich, Germany; Institute of Human Genetics,
Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg,
Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany.
[88
]
Duke Molecular Physiology Institute, Duke University, Durham, North Carolina; Division
of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.
[89
]
Department of Clinical Sciences in Malmo, Lund University, Clinical Research Center,
Malmo, Sweden.
[90
]
Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, University
Hospital Malmo, Malmo, Sweden.
[91
]
DZHK, Partner Site Munich Heart Alliance, Munich, Germany; Institute of Epidemiology
II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg,
Germany.
[92
]
Department of Genetics, Cardiovascular Institute and Institute of Translational Medicine
and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
Pennsylvania.
[93
]
Division of Cardiology, Department of Medicine and the Irving Institute for Clinical
and Translational Research, Columbia University, New York, New York.
[94
]
The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine
at Mount Sinai, New York, New York; The Genetics of Obesity and Related Metabolic
Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York; The
Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount
Sinai, New York, New York.
[95
]
Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Epidemiology,
University of Washington, Seattle, Washington.
[96
]
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee;
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee.
[97
]
NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester,
United Kingdom; Department of Health Sciences, University of Leicester, Leicester,
United Kingdom.
[98
]
Université de Montréal, Faculté de médecine, Département de médecine, Montreal, Quebec,
Canada; Department of Computational Medicine and Bioinformatics, University of Michigan,
Ann Arbor, Michigan; Department of Human Genetics, University of Michigan, Ann Arbor,
Michigan.
[99
]
Department of Cardiovascular Sciences, University of Leicester, Leicester, United
Kingdom; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital,
Leicester, United Kingdom. Electronic address: njs@le.ac.uk.
[100
]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry,
Queen Mary University of London, London, United Kingdom; Princess Al-Jawhara Al-Brahim
Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz
University, Jeddah, Saudi Arabia. Electronic address: p.deloukas@qmul.ac.uk.
[101
]
Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts;
Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts;
Department of Medicine, Harvard Medical School, Boston, Massachusetts; Program in
Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; Cardiology
Division, Massachusetts General Hospital, Boston, Massachusetts.