Anti-interleukin 1 agents for the treatment of recurrent pericarditis: a systematic review and meta-analysis.

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Abstract

Corticosteroid-dependent and colchicine-resistant recurrent pericarditis (RP) is a challenging management problem, in which conventional anti-inflammatory therapy (nonsteroidal anti-inflammatory drugs, colchicine, corticosteroids) is unable to control the disease. Recent data suggest a potential role for anti-interleukin-1 (IL-1) agents for this condition. This study was designed to assess the safety and efficacy of anti-IL-1 agents in this setting.

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Journal

Journal ID (iso-abbrev): Heart

Title: Heart (British Cardiac Society)

Publisher: BMJ

ISSN (Electronic): 1468-201X

ISSN (Print): 1355-6037

Publication date (Electronic): Mar 18 2021

Affiliations

[1 ] University Cardiology, Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, Torino, Italy massimo_imazio@yahoo.it.

[2 ] Department of Public Health and Pediatrics, University of Turin, Torino, Italy.

[3 ] Department of Medical Sciences, Division of Cardiology, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.

[4 ] Cardiology, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital, Athens, Greece.

[5 ] Istituto Pediatrico di Ricovero e Cura a Carattere Scientifico, Giannina Gaslini, Genova, Liguria, Italy.

[6 ] Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.

[7 ] Department of Cardiovascular Medicine, Center for the Diagnosis and Treatment of Pericardial Diseases, Section of Cardiovascular Imaging, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.

[8 ] Department of Biomedical and Clinical Sciences, Fatebenefratelli Hospital, University of Milan, Milano, Italy.

Article

Publisher Item ID: heartjnl-2020-318869

DOI: 10.1136/heartjnl-2020-318869

PubMed ID: 33737453

SO-VID: 4008ec11-e150-422f-9a6e-ec243da0f511

History

Keywords: pericarditis

Data availability:

Keywords: pericarditis

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