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      The comprehensive complication index: a novel and more sensitive endpoint for assessing outcome and reducing sample size in randomized controlled trials.

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          Abstract

          To test whether the newly developed comprehensive complication index (CCI) is more sensitive than traditional endpoints for detecting between-group differences in randomized controlled trials (RCTs).

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          Author and article information

          Journal
          Ann. Surg.
          Annals of surgery
          1528-1140
          0003-4932
          Nov 2014
          : 260
          : 5
          Affiliations
          [1 ] *Department of Surgery and Transplantation, University Hospital of Zurich, Zurich, Switzerland †Department of Surgery, Division of Gastrointestinal and Transplantation Surgery, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands ‡Pôle des Pathologies Digestives, Hépatiques et de la Transplantation, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France §Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland. ¶Hospital Paul Brousse, Université Paris Sud, Paris, France.
          Article
          00000658-201411000-00006
          10.1097/SLA.0000000000000948
          25379846
          1771bd69-48d2-4e3e-85b3-11c036d61941
          History

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