Evolving Developments in Cardiac CT

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<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d8960791e59">In this review, the authors describe some of the latest cardiac CT advances in the evaluation of cardiovascular disease. This includes automated coronary plaque quantification and subtyping, and cardiac CT fractional flow reserve and CT perfusion as techniques to noninvasively assess the physiologic significance of coronary stenosis. The authors also focus on noncoronary applications involving the expanding role of cardiac CT in structural heart disease interventions. Developments in cardiac CT for the evaluation of diffuse myocardial fibrosis and infiltrative cardiomyopathy and for functional analysis of myocardial contractile dysfunction are discussed. Finally, the authors review studies evaluating photon-counting CT in cardiac disease. </p>

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Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI)

Daniel R Messroghli, James Moon, Vanessa M. Ferreira … (2017)

Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR). Parametric mapping with CMR now permits the routine spatial visualization and quantification of changes in myocardial composition based on changes in T1, T2, and T2*(star) relaxation times and extracellular volume (ECV). These changes include specific disease pathways related to mainly intracellular disturbances of the cardiomyocyte (e.g., iron overload, or glycosphingolipid accumulation in Anderson-Fabry disease); extracellular disturbances in the myocardial interstitium (e.g., myocardial fibrosis or cardiac amyloidosis from accumulation of collagen or amyloid proteins, respectively); or both (myocardial edema with increased intracellular and/or extracellular water). Parametric mapping promises improvements in patient care through advances in quantitative diagnostics, inter- and intra-patient comparability, and relatedly improvements in treatment. There is a multitude of technical approaches and potential applications. This document provides a summary of the existing evidence for the clinical value of parametric mapping in the heart as of mid 2017, and gives recommendations for practical use in different clinical scenarios for scientists, clinicians, and CMR manufacturers.

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Coronary CT Angiography and 5-Year Risk of Myocardial Infarction

(2018)

Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.

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Prognostic implications of global LV dysfunction: a systematic review and meta-analysis of global longitudinal strain and ejection fraction.

Kashif Kalam, Petr Otahal, Thomas H. Marwick (2014)

Global longitudinal strain (GLS) is a robust, well validated and reproducible technique for the measurement of LV longitudinal deformation. We sought to assemble evidence that GLS is an accurate marker in predicting cardiovascular outcomes, compared to LVEF.

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Jonathan D. Dodd: (View ORCID Profile)

Jonathan A. Leipsic: (View ORCID Profile)

Journal

Title: Radiology

Abbreviated Title: Radiology

Publisher: Radiological Society of North America (RSNA)

ISSN (Print): 0033-8419

ISSN (Electronic): 1527-1315

Publication date Created: May 01 2023

Publication date (Print): May 01 2023

Volume: 307

Issue: 3

Affiliations

[1 ]From the Department of Radiology, St Vincent’s University Hospital, Elm Park, Dublin 4, Ireland (J.D.D.); School of Medicine, University College Dublin, Dublin, Ireland (J.D.D.); and Department of Radiology, St Paul’s Hospital, University of British Columbia, Vancouver, Canada (J.A.L.).

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DOI: 10.1148/radiol.222827

SO-VID: e23799d1-b861-4e10-a69c-2d1b9b404608

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Evolving Developments in Cardiac CT

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Radiology Science

Most cited references 83

Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI)

Coronary CT Angiography and 5-Year Risk of Myocardial Infarction

Prognostic implications of global LV dysfunction: a systematic review and meta-analysis of global longitudinal strain and ejection fraction.

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