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      Epidemiology of comorbidities and their association with asthma control.

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          Abstract

          The prevalence of comorbidities and their relation to asthma control and treatment is a topic of increasing interest, however comprehensive studies are scarce. We aimed to determine the prevalence of the most common comorbidities in asthma in relation to patient characteristics (age, gender and body mass index [BMI]) and their association with asthma control in a large, specialist-managed representative patient population.

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          Most cited references22

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          2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

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            Ageing and the epidemiology of multimorbidity.

            The world's population is ageing and an important part of this demographic shift is the development of chronic illness. In short, a person who does not die of acute illnesses, such as infections, and survives with chronic illnesses is more likely to develop additional chronic illnesses. Chronic respiratory diseases are an important component of these diseases associated with ageing. This article reviews the relationship between ageing and chronic respiratory disease, and also how certain chronic diseases cluster with others, either on the basis of underlying risk factors, complication of the primary disease or other factors, such as an increased state of inflammation. While death is inevitable, disabling chronic illnesses are not. Better understanding of how individuals can age healthily without the development of multiple chronic illnesses should lead to an improved global quality of life.
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              Presentation and Epidemiology of Gastroesophageal Reflux Disease

              Gastroesophageal reflux disease (GERD) is the most prevalent gastrointestinal disorder in the United States, and leads to substantial morbidity, though associated mortality is rare. The prevalence of GERD symptoms appeared to increase until 1999. Risk factors for complications of GERD include advanced age, male sex, white race, abdominal obesity, and tobacco use. Most patients with GERD present with heartburn and effortless regurgitation. Coexistent dysphagia is considered an alarm symptom, prompting evaluation. There is substantial overlap between symptoms of GERD and those of eosinophilic esophagitis, functional dyspepsia, and gastroparesis, posing a challenge for patient management.
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                Author and article information

                Journal
                Allergy Asthma Clin Immunol
                Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
                Springer Science and Business Media LLC
                1710-1484
                1710-1484
                Sep 22 2021
                : 17
                : 1
                Affiliations
                [1 ] Chiesi Hungary Ltd, Budapest, 1138, Hungary. g.tomisa@chiesi.com.
                [2 ] Department of Pulmonology, Semmelweis University, Tömő u. 25-29, Budapest, 1083, Hungary. g.tomisa@chiesi.com.
                [3 ] Chiesi Hungary Ltd, Budapest, 1138, Hungary.
                [4 ] Department of Pulmonology, Semmelweis University, Tömő u. 25-29, Budapest, 1083, Hungary.
                Article
                10.1186/s13223-021-00598-3
                10.1186/s13223-021-00598-3
                8459511
                34551813
                774d69f4-7fa3-4210-bc1e-ff2ba9a6a950
                History

                Comorbidities,Gender,Age,Asthma,Asthma control,BMI
                Comorbidities, Gender, Age, Asthma, Asthma control, BMI

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