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      Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

      review-article
      1 , 39 , , 1 , 2 , 3 , 4 , 3 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 21 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 1
      World Journal of Emergency Surgery : WJES
      BioMed Central
      Small bowel obstruction, Adhesions, Surgery, Laparoscopy, Laparotomy

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          Abstract

          Background

          Adhesive small bowel obstruction (ASBO) is a common surgical emergency, causing high morbidity and even some mortality. The adhesions causing such bowel obstructions are typically the footprints of previous abdominal surgical procedures. The present paper presents a revised version of the Bologna guidelines to evidence-based diagnosis and treatment of ASBO. The working group has added paragraphs on prevention of ASBO and special patient groups.

          Methods

          The guideline was written under the auspices of the World Society of Emergency Surgery by the ASBO working group. A systematic literature search was performed prior to the update of the guidelines to identify relevant new papers on epidemiology, diagnosis, and treatment of ASBO. Literature was critically appraised according to an evidence-based guideline development method. Final recommendations were approved by the workgroup, taking into account the level of evidence of the conclusion.

          Recommendations

          Adhesion formation might be reduced by minimally invasive surgical techniques and the use of adhesion barriers. Non-operative treatment is effective in most patients with ASBO. Contraindications for non-operative treatment include peritonitis, strangulation, and ischemia. When the adhesive etiology of obstruction is unsure, or when contraindications for non-operative management might be present, CT is the diagnostic technique of choice. The principles of non-operative treatment are nil per os, naso-gastric, or long-tube decompression, and intravenous supplementation with fluids and electrolytes. When operative treatment is required, a laparoscopic approach may be beneficial for selected cases of simple ASBO.

          Younger patients have a higher lifetime risk for recurrent ASBO and might therefore benefit from application of adhesion barriers as both primary and secondary prevention.

          Discussion

          This guideline presents recommendations that can be used by surgeons who treat patients with ASBO. Scientific evidence for some aspects of ASBO management is scarce, in particular aspects relating to special patient groups. Results of a randomized trial of laparoscopic versus open surgery for ASBO are awaited.

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          Most cited references94

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          What is "quality of evidence" and why is it important to clinicians?

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            Going from evidence to recommendations.

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              Burden of adhesions in abdominal and pelvic surgery: systematic review and met-analysis

              Objective To estimate the disease burden of the most important complications of postoperative abdominal adhesions: small bowel obstruction, difficulties at reoperation, infertility, and chronic pain. Design Systematic review and meta-analyses. Data sources Searches of PubMed, Embase, and Central, from January 1990 to December 2012, without restrictions to publication status or language. Study selection All types of studies reporting on the incidence of adhesion related complications were considered. Data extraction and analysis The primary outcome was the incidence of adhesive small bowel obstruction in patients with a history of abdominal surgery. Secondary outcomes were the incidence of small bowel obstruction by any cause, difference in operative time, enterotomy during adhesiolysis, and pregnancy rate after abdominal surgery. Subgroup and sensitivity analyses were done to study the robustness of the results. A random effects model was used to account for heterogeneity between studies. Results We identified 196 eligible papers. Heterogeneity was considerable for almost all meta-analyses. The origin of heterogeneity could not be explained by study design, study quality, publication date, anatomical site of operation, or operative technique. The incidence of small bowel obstruction by any cause after abdominal surgery was 9% (95% confidence interval 7% to 10%; I2=99%). the incidence of adhesive small bowel obstruction was 2% (2% to 3%; I2=93%); presence of adhesions was generally confirmed by emergent reoperation. In patients with a known cause of small bowel obstruction, adhesions were the single most common cause (56%, 49% to 64%; I2=96%). Operative time was prolonged by 15 minutes (95% confidence interval 9.3 to 21.1 minutes; I2=85%) in patients with previous surgery. Use of adhesiolysis resulted in a 6% (4% to 8%; I2=89%) incidence of iatrogenic bowel injury. The pregnancy rate after colorectal surgery in patients with inflammatory bowel disease was 50% (37% to 63%; I2=94%), which was significantly lower than the pregnancy rate in medically treated patients (82%, 70% to 94%; I2=97%). Conclusions This review provides detailed and systematically analysed knowledge of the disease burden of adhesions. Complications of postoperative adhesion formation are frequent, have a large negative effect on patients’ health, and increase workload in clinical practice. The quantitative effects should be interpreted with caution owing to large heterogeneity. Registration The review protocol was registered through PROSPERO (CRD42012003180).
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                Author and article information

                Contributors
                +31-243610903 , Richard.tenbroek@radboudumc.nl , http://www.dutchadhesiongroup.org
                Pepijn.krielen@radboudumc.nl
                salo75@inwind.it
                federico.coccolini@gmail.com
                walt@biffl.com
                lansaloni@hpg23.it
                gvelmahos@partners.org
                massimosartelli@gmail.com
                fragagp2008@gmail.com
                mk@mdkelly.com
                Frederick.Moore@surgery.ufl.edu
                peitzmanab@msx.upmc.edu
                ari.leppaniemi@hus.fi
                ernest.moore@dhha.org
                j.jeekel@erasmusmc.nl
                y_kluger@rambam.health.gov.il
                Michael.Sugrue@hse.ie
                zsolt.balogh@hnehealth.nsw.gov.au
                Cino.Bendinelli@hnehealth.nsw.gov.au
                icivil@xtra.co.nz
                rcoimbra@ucsd.edu
                mdemoya@mgh.harvard.edu
                paula.ferrada@vcuhealth.org
                kenji.inaba@med.usc.edu
                raoivatury@gmail.com
                rlatifi@email.arizona.edu
                jeffrykashuk@gmail.com
                Andrew.Kirkpatrick@albertahealthservices.ca
                ronmaier@uw.edu
                rizolis@smh.ca
                bsakakushev@gmail.com
                tscalea@umm.edu
                ksoreide@mac.com
                dweber@bigpond.net.au
                mtazwani@gmail.com
                fabuzidan@uaeu.ac.ae
                nic.deangelis@yahoo.it
                frank.piscioneri@act.gov.au
                jmgalante@ucdavis.edu
                faustocatena@gmail.com
                Harry.vanGoor@radboudumc.nl
                Journal
                World J Emerg Surg
                World J Emerg Surg
                World Journal of Emergency Surgery : WJES
                BioMed Central (London )
                1749-7922
                19 June 2018
                19 June 2018
                2018
                : 13
                : 24
                Affiliations
                [1 ]ISNI 0000 0004 0444 9382, GRID grid.10417.33, Department of Surgery, , Radboud University Medical Center, ; Nijmegen, The Netherlands
                [2 ]ISNI 0000 0004 0622 5016, GRID grid.120073.7, Addenbrooke’s Hospital, ; Cambridge, UK
                [3 ]ISNI 0000 0004 1758 8744, GRID grid.414682.d, General Emergency and Trauma Surgery, , Bufalini hospital, ; Cesena, Italy
                [4 ]GRID grid.415594.8, Acute Care Surgery, , The Queen’s Medical Center, ; Honolulu, Hawaii USA
                [5 ]ISNI 0000 0004 0386 9924, GRID grid.32224.35, Department of Trauma, Emergency Surgery and Surgical Critical Care, , Massachusetts General Hospital, ; Boston, MA USA
                [6 ]Department of Surgery, Macerata Hospital, Macerata, Italy
                [7 ]Faculdade de Ciências Médicas (FCM), Unicamp Campinas, São Paulo, Brazil
                [8 ]Albury Hospital, Albury, NSW Australia
                [9 ]ISNI 0000 0004 1936 8091, GRID grid.15276.37, University of Florida, ; Gainesville, USA
                [10 ]ISNI 0000 0004 1936 9000, GRID grid.21925.3d, Department of Surgery, Trauma and Surgical Services, , University of Pittsburgh School of Medicine, ; Pittsburgh, USA
                [11 ]Second Department of Surgery, Meilahti Hospital, Helsinki, Finland
                [12 ]ISNI 0000 0001 0369 638X, GRID grid.239638.5, Trauma Surgery, , Denver Health, ; Denver, CO USA
                [13 ]ISNI 000000040459992X, GRID grid.5645.2, Erasmus MC, ; Rotterdam, The Netherlands
                [14 ]Division of General Surgery Rambam Health Care Campus Haifa, Haifa, Israel
                [15 ]General Surgery Department, Letterkenny Hospital, Letterkenny, Ireland
                [16 ]ISNI 0000 0004 0577 6676, GRID grid.414724.0, Department of Traumatology, , John Hunter Hospital and University of Newcastle, ; Newcastle, NSW Australia
                [17 ]John Hunter Hospital, New Lambton Heights, New Zealand
                [18 ]ISNI 0000 0000 9027 2851, GRID grid.414055.1, Department of Vascular and Trauma Surgery, , Auckland City Hospital, ; Auckland, New Zealand
                [19 ]GRID grid.420234.3, Department of Surgery, , UC San Diego Health System, ; San Diego, USA
                [20 ]Trauma, Acute Care Surgery Medical College of Wisconsin/Froedtert Trauma Center Milwaukee, Milwaukee, Wisconsin USA
                [21 ]ISNI 0000 0004 0458 8737, GRID grid.224260.0, Virginia Commonwealth University, ; Richmond, VA USA
                [22 ]ISNI 0000 0001 2156 6853, GRID grid.42505.36, Division of Trauma & Critical Care, LAC+USC Medical Center, , University of Southern California, ; Los Angeles, CA USA
                [23 ]ISNI 0000 0004 0476 8324, GRID grid.417052.5, Department of General Surgery, , Westchester Medical Center, ; Westchester, NY USA
                [24 ]ISNI 0000 0004 0644 9941, GRID grid.414003.2, Department of General Surgery, , Assuta Medical Centers, ; Tel Aviv, Israel
                [25 ]ISNI 0000 0004 0469 2139, GRID grid.414959.4, Department of Surgery, , Foothills Medical Centre, ; Calgary, Canada
                [26 ]Department of Surgery, Harborview Medical Centre, Seattle, USA
                [27 ]GRID grid.415502.7, Trauma & Acute Care Service, , St Michael’s Hospital, ; Toronto, ON Canada
                [28 ]ISNI 0000 0001 1014 775X, GRID grid.11187.3e, Department of General Surgery, , University of Medicine Plovdiv, ; Plovdiv, Bulgaria
                [29 ]ISNI 0000 0001 2175 4264, GRID grid.411024.2, R Adams Crowley Shock Trauma Center, , University of Maryland, ; Baltimore, USA
                [30 ]ISNI 0000 0004 0627 2891, GRID grid.412835.9, Department of Gastrointestinal Surgery, , Stavanger University Hospital, ; Stavanger, Norway
                [31 ]ISNI 0000 0004 1936 7443, GRID grid.7914.b, Department of Clinical Medicine, , University of Bergen, ; Bergen, Norway
                [32 ]ISNI 0000 0004 1936 7910, GRID grid.1012.2, Department of General Surgery, Royal Perth Hospital, , The University of Western Australia and The University of Newcastle, ; Perth, Australia
                [33 ]ISNI 0000 0001 0174 2901, GRID grid.414739.c, Department of Surgery, , Sheri-Kashmir Institute of Medical Sciences, ; Srinagar, India
                [34 ]ISNI 0000 0001 2193 6666, GRID grid.43519.3a, Department of Surgery, College of Medicine and Health Sciences, , UAE University, ; Al-Ain, United Arab Emirates
                [35 ]ISNI 0000 0001 2292 1474, GRID grid.412116.1, Unit of Digestive Surgery, HPB Surgery and Liver Transplant, , Henri Mondor Hospital, ; Créteil, France
                [36 ]ISNI 0000 0000 9984 5644, GRID grid.413314.0, Canberra Hospital, ; Canberra, Australia
                [37 ]ISNI 0000 0004 1936 9684, GRID grid.27860.3b, Trauma and Acute Care Surgery and Surgical Critical Care Trauma, Department of Surgery, , University of California, ; Davis, USA
                [38 ]Emergency and Trauma Surgery, Parma Maggiore hospital, Parma, Italy
                [39 ]ISNI 0000 0004 0444 9382, GRID grid.10417.33, Department of Surgery, , Radboud University Nijmegen Medical Centre, ; P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
                Article
                185
                10.1186/s13017-018-0185-2
                6006983
                394918fa-874a-4e5c-983f-681ac4c1051a
                © The Author(s). 2018

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 19 January 2018
                : 29 May 2018
                Categories
                Review
                Custom metadata
                © The Author(s) 2018

                Surgery
                small bowel obstruction,adhesions,surgery,laparoscopy,laparotomy
                Surgery
                small bowel obstruction, adhesions, surgery, laparoscopy, laparotomy

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