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      Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation: A Randomized Clinical Trial.

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          Abstract

          Outcomes after exacerbations of chronic obstructive pulmonary disease (COPD) requiring acute noninvasive ventilation (NIV) are poor and there are few treatments to prevent hospital readmission and death.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          1538-3598
          0098-7484
          May 21 2017
          Affiliations
          [1 ] Lane Fox Unit, Guy's and St Thomas' NHS Foundation Trust, London, England2Asthma, Allergy, and Lung Biology, King's College London, London, England.
          [2 ] MRC Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, England.
          [3 ] Lane Fox Unit, Guy's and St Thomas' NHS Foundation Trust, London, England.
          [4 ] Respiratory Medicine, Northumbria Healthcare NHS Foundation Trust, Newcastle, England5Institute of Cellular Medicine, Newcastle University, Newcastle, England.
          [5 ] School of Aging and Chronic Disease, University of Liverpool, Liverpool, England.
          [6 ] Respiratory Medicine, Royal Wolverhampton NHS Trust, Wolverhampton, England.
          [7 ] Respiratory Medicine, Aintree University Hospital, Liverpool, England.
          [8 ] Respiratory Medicine, Newcastle University, Newcastle, England.
          [9 ] Respiratory Medicine, Plymouth Hospital NHS Trust, Plymouth, England.
          [10 ] Respiratory Medicine, University College London, Royal Free Campus, London, England.
          [11 ] Respiratory Medicine, Swansea University, Swansea, England.
          [12 ] Respiratory Medicine, Heart of England NHS Trust, Birmingham, England.
          [13 ] Oxford NIHR Biomedical Research Centre, Oxford University and NHS Foundation Trust, Oxford, England.
          [14 ] Respiratory Support and Centre, Papworth Hospital, Cambridge, England.
          [15 ] Respiratory Medicine, Taunton and Somerset NHS Trust, Taunton, England.
          [16 ] NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, England.
          [17 ] Department of Respiratory Medicine, Leeds University Hospital, Leeds, England.
          Article
          2627985
          10.1001/jama.2017.4451
          28528348
          8debd454-7e8a-4e41-a486-e54578bdfd05
          History

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