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      Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial.

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          Abstract

          Agitation is common among patients with Alzheimer disease; safe, effective treatments are lacking.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          1538-3598
          0098-7484
          September 24 2015
          : 314
          : 12
          Affiliations
          [1 ] Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Nevada.
          [2 ] Johns Hopkins Memory and Alzheimer's Treatment Center, Johns Hopkins Bayview, Baltimore, Maryland.
          [3 ] VA Puget Sound Health Care System, University of Washington School of Medicine, Seattle.
          [4 ] University of Rochester School of Medicine and Dentistry, Rochester, New York.
          [5 ] Clinical Biotechnology Research Institute, Roper St Francis Hospital, Charleston, South Carolina6Ralph H. Johnson VA Medical Center, Charleston, South Carolina.
          [6 ] Ohio State University, Columbus.
          [7 ] Quantum Laboratories Inc, West Palm Beach, Florida.
          [8 ] Miami Jewish Health Systems, Miami, Florida.
          [9 ] CSD Biostatistics Inc, Tucson, Arizona.
          [10 ] Avanir Pharmaceuticals Inc, Aliso Viejo, California.
          [11 ] Banner Alzheimer's Institute, Phoenix, Arizona.
          Article
          2442936
          10.1001/jama.2015.10214
          26393847
          198cb435-f58d-4fc2-9705-23cc026b697d
          History

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