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      What we can do and what we cannot do with fMRI

      Nature
      Springer Science and Business Media LLC

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          Abstract

          Functional magnetic resonance imaging (fMRI) is currently the mainstay of neuroimaging in cognitive neuroscience. Advances in scanner technology, image acquisition protocols, experimental design, and analysis methods promise to push forward fMRI from mere cartography to the true study of brain organization. However, fundamental questions concerning the interpretation of fMRI data abound, as the conclusions drawn often ignore the actual limitations of the methodology. Here I give an overview of the current state of fMRI, and draw on neuroimaging and physiological data to present the current understanding of the haemodynamic signals and the constraints they impose on neuroimaging data interpretation.

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          Author and article information

          Journal
          Nature
          Nature
          Springer Science and Business Media LLC
          0028-0836
          1476-4687
          June 2008
          June 2008
          : 453
          : 7197
          : 869-878
          Article
          10.1038/nature06976
          5fe64111-53e8-434b-8cde-a2dd21d289c7
          © 2008

          http://www.springer.com/tdm

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