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      Rechallenge with oxaliplatin and peripheral neuropathy in colorectal cancer patients.

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          Abstract

          Oxaliplatin (OXA) is a cornerstone in the treatment of colorectal cancer (CRC). Retreatment with OXA is frequently considered as salvage treatment. OXA-induced neuropathy (OIN) is the most frequent and feared long-term side effect.

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          Author and article information

          Journal
          J Cancer Res Clin Oncol
          Journal of cancer research and clinical oncology
          Springer Science and Business Media LLC
          1432-1335
          0171-5216
          Sep 2018
          : 144
          : 9
          Affiliations
          [1 ] Neuro-Oncology Unit, Neurology Department, Hospital Universitari de Bellvitge-Institut Català d´Oncologia-IDIBELL, C/Feixa Llarga s/n, L´Hospitalet de Llobregat, 08907, Barcelona, Spain.
          [2 ] Neurology Department, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain.
          [3 ] Medical Oncology Department, Institut Català d´Oncologia-IDIBELL, CIBERONC, L'Hospitalet de Llobregat, Barcelona, Spain.
          [4 ] Service de Neuro-Oncologie, Hospices Civils de Lyon, Groupe Hospitalier Est, Lyon Cedex, France.
          [5 ] Department of Cell Biology, Physiology and Immunology, Institute of Neurosciences, Universitat Autònoma de Barcelona, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Bellaterra, Spain.
          [6 ] Neuro-Oncology Unit, Neurology Department, Hospital Universitari de Bellvitge-Institut Català d´Oncologia-IDIBELL, C/Feixa Llarga s/n, L´Hospitalet de Llobregat, 08907, Barcelona, Spain. rvelascof@bellvitgehospital.cat.
          [7 ] Department of Cell Biology, Physiology and Immunology, Institute of Neurosciences, Universitat Autònoma de Barcelona, and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Bellaterra, Spain. rvelascof@bellvitgehospital.cat.
          Article
          10.1007/s00432-018-2691-8
          10.1007/s00432-018-2691-8
          29955956
          53f1d18f-a008-4281-8faa-c57d249009de
          History

          Neurotoxicity,FOLFOX,Oxaliplatin,Oxaliplatin-induced neuropathy,Retreatment

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