Jay Ghurye:
ORCID: http://orcid.org/0000-0003-1381-4081
Role: MethodologyRole: SoftwareRole: VisualizationRole: Writing – original draftRole:
Writing – review & editing
Arang Rhie:
ORCID: http://orcid.org/0000-0002-9809-8127
Role: Formal analysisRole: MethodologyRole: Writing – original draftRole: Writing
– review & editing
Brian P. Walenz:
ORCID: http://orcid.org/0000-0001-8431-1428
Role: Data curationRole: Writing – original draftRole: Writing – review & editing
Anthony Schmitt: Role: Data curationRole: Writing – review & editing
Siddarth Selvaraj: Role: Data curationRole: Writing – review & editing
Mihai Pop:
ORCID: http://orcid.org/0000-0001-9617-5304
Role: SupervisionRole: Writing – review & editing
Adam M. Phillippy:
ORCID: http://orcid.org/0000-0003-2983-8934
Role: InvestigationRole: SupervisionRole: Writing – original draftRole: Writing –
review & editing
Sergey Koren:
ORCID: http://orcid.org/0000-0002-1472-8962
Role: InvestigationRole: SoftwareRole: ValidationRole: Writing – original draftRole:
Writing – review & editing
Ilya Ioshikhes: Role: Editor
Journal ID (nlm-ta): PLoS Comput Biol
Journal ID (iso-abbrev): PLoS Comput. Biol
Journal ID (publisher-id): plos
Journal ID (pmc): ploscomp
Title:
PLoS Computational Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-734X
ISSN
(Electronic):
1553-7358
Publication date Collection:
August
2019
Publication date
(Electronic):
21
August
2019
Volume: 15
Issue: 8
Electronic Location Identifier: e1007273
Affiliations
[1
]
Department of Computer Science, University of Maryland, College Park, Maryland, United
States of America
[2
]
Genome Informatics Section, Computational and Statistical Genomics Branch, National
Human Genome Research Institute, National Institute of Health, Bethesda, Maryland,
United States of America
[3
]
Arima Genomics, San Diego, California, United States of America
Ottawa University, CANADA
Author notes
Sergey Koren has received travel and accommodation expenses to speak at Oxford Nanopore
Technologies conferences. Anthony Schmitt and Siddarth Selvaraj are employees of Arima
Genomics, a company commercializing Hi-C DNA sequencing technologies.
Author information
Article
Publisher ID:
PCOMPBIOL-D-19-00061
DOI: 10.1371/journal.pcbi.1007273
PMC ID: 6719893
PubMed ID: 31433799
SO-VID: d4877977-d1ad-4170-9c04-3c4068e72948
License:
This is an open access article, free of all copyright, and may be freely reproduced,
distributed, transmitted, modified, built upon, or otherwise used by anyone for any
lawful purpose. The work is made available under the
Creative Commons CC0 public domain dedication.
The funders had no role in study design, data collection and analysis, decision to
publish, or preparation of the manuscript. AS and SS were funded by generous support
from NHGRI (grant\# 1R44HG009584). JG and MP were supported by NIH grant R01-AI-100947
to MP. SK, AR, BPW, and AMP were supported by the Intramural Research Program of the
National Human Genome Research Institute, National Institutes of Health. AR was also
supported by a grant from the Korean Visiting Scientist Training Award (KVSTA) through
the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of
Health \& Welfare, Republic of Korea (grant number: HI17C2098). This work utilized
the computational resources of the NIH HPC Biowulf cluster (
http://hpc.nih.gov).
Subject:
Research Article
Subject:
Computer and Information Sciences
Subject:
Data Visualization
Subject:
Infographics
Subject:
Graphs
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Analysis
Subject:
Genomic Libraries
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Analysis
Subject:
Genomic Libraries
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Analysis
Subject:
Sequence Assembly Tools
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Analysis
Subject:
Sequence Assembly Tools
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Alignment
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Gene Mapping
Subject:
Chromosome Mapping
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Gene Mapping
Subject:
Chromosome Mapping
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genomics Statistics
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genomics Statistics
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Sequencing Techniques
Subject:
Genome Sequencing
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Sequencing Techniques
Subject:
Genome Sequencing
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genetic Loci