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      The change of myopic prevalence in children and adolescents before and after COVID-19 pandemic in Suqian, China

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          Abstract

          Purpose

          The aim of this study was to investigate the change of myopic prevalence in students with different demographic characteristics before and after the COVID-19 pandemic in Suqian, China.

          Methods

          A retrospective, cross-sectional study was conducted. Student data from 52 schools in 2019 and 2020 were collected from the electronic medical records database through cluster sampling. Ophthalmic examinations were conducted on students from September to December in 2019 and 2020. Measurements of uncorrected visual acuity (UCVA) and noncycloplegic autorefraction were included to obtain the spherical equivalent refraction (SER) and prevalence of myopia. The difference in the rate of myopia and SER of students ages 6 to 18 with various demographic characteristics was compared between the two years.

          Results

          Records from 118,479 students in 2019 and the 121,881 students in 2020 were obtained. In 2019 and 2020, the prevalence of overall myopia increased from 43.1% to 48.9% (5.8 percentage point), and a substantial shift in myopic rate occurred in grades 4 to 6 (6.9 percentage point). The change in the prevalence of myopia in girls (5.9 percentage point) was approximately equal to that in boys (5.8 percentage point) and it was more common in rural students (5.9 percentage point) than in urban students (5.1 percentage point). The prevalence of low myopia increased more in children, and the prevalence of moderate myopia increased more in adolescents. The mean spherical equivalent refraction (SER) (-1.34±2.03 D) was lower in 2020 than in 2019 (-1.16±1.92 D), while SER decreased mainly at ages 7 to 15. The SER presented myopic status at the age of 9 (-0.55±1.26 D in 2019, -0.71±1.42 D in 2020), and attained moderate myopia at the age of 15 (-3.06±2.41 D in 2019, -3.22±2.40 D in 2020).

          Conclusions

          After the COVID-19 pandemic, myopia increased in this population with variable rates of increase in different demographic groups. The change of myopia in children was comparatively greater than that in adolescents. Therefore, we should take measures to prevent and control the development of myopia after the COVID-19 pandemic, especially for younger students.

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          Most cited references39

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          Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050.

          Myopia is a common cause of vision loss, with uncorrected myopia the leading cause of distance vision impairment globally. Individual studies show variations in the prevalence of myopia and high myopia between regions and ethnic groups, and there continues to be uncertainty regarding increasing prevalence of myopia.
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            Mitigate the effects of home confinement on children during the COVID-19 outbreak

            In response to the coronavirus disease 2019 (COVID-19) outbreak, the Chinese Government has ordered a nationwide school closure as an emergency measure to prevent spreading of the infection. Public activities are discouraged. The Ministry of Education estimates that more than 220 million children and adolescents are confined to their homes; this includes 180 million primary and secondary students and 47 million preschool children). 1 Thanks to the strong administrative system in China, the emergency home schooling plan has been rigorously implemented. 2 Massive efforts are being made by schools and teachers at all levels to create online courses and deliver them through TV broadcasts and the internet in record time. The new virtual semester has just started in many parts of the country, and various courses are offered online in a well organised manner. These actions are helping to alleviate many parents' concerns about their children's educational attainment by ensuring that school learning is largely undisrupted. Although these measures and efforts are highly commendable and necessary, there are reasons to be concerned because prolonged school closure and home confinement during a disease outbreak might have negative effects on children's physical and mental health.3, 4 Evidence suggests that when children are out of school (eg, weekends and summer holidays), they are physically less active, have much longer screen time, irregular sleep patterns, and less favourable diets, resulting in weight gain and a loss of cardiorespiratory fitness.3, 5 Such negative effects on health are likely to be much worse when children are confined to their homes without outdoor activities and interaction with same aged friends during the outbreak. Perhaps a more important but easily neglected issue is the psychological impact on children and adolescents. Stressors such as prolonged duration, fears of infection, frustration and boredom, inadequate information, lack of in-person contact with classmates, friends, and teachers, lack of personal space at home, and family financial loss can have even more problematic and enduring effects on children and adolescents. 4 For example, Sprang and Silman 6 showed that the mean posttraumatic stress scores were four times higher in children who had been quarantined than in those who were not quarantined. Furthermore, the interaction between lifestyle changes and psychosocial stress caused by home confinement could further aggravate the detrimental effects on child physical and mental health, which could cause a vicious circle. To mitigate the consequences of home confinement, the government, non-governmental organisations (NGOs), the community, school, and parents need to be aware of the downside of the situation and do more to effectively address these issues immediately. Experiences learned from previous outbreaks can be valuable for designing a new programme to tackle these issues in China. 7 The Chinese Government needs to raise the awareness of potential physical and mental health impacts of home confinement during this unusual period. The government should also provide guidelines and principles in effective online learning and ensure that the contents of the courses meet the educational requirements. Yet it is also important not to overburden the students. The government might mobilise existing resources, perhaps involving NGOs, and create a platform for gathering the best online education courses about healthy lifestyle and psychosocial support programmes available for schools to choose from. For example, in addition to innovative courses for a better learning experience, promotional videos can be useful to motivate children to have a healthy lifestyle at home by increasing physical activities, having a balanced diet, regular sleep pattern, and good personal hygiene. 8 To make these educational materials truly effective, they must be age-appropriate and attractive. They require professional expertise and real resources to create. Communities can serve as valuable resources in managing difficulties of family matters. For instance, parents' committees can work together to bridge the needs of students with school requirements and to advocate for children's rights to a healthy lifestyle. Psychologists can provide online services to cope with mental health issues caused by domestic conflicts, tension with parents, and anxiety from becoming infected. 7 Social workers can play an active role in helping parents cope with family issues arising from the situation, when needed. Such a social safety net could be particularly useful for disadvantaged or single-parent families, 9 but action is needed to make it accessible to them. Schools have a critical role, not only in delivering educational materials to children, but in offering an opportunity for students to interact with teachers and obtain psychological counselling. Schools can actively promote a health-conscious schedule, good personal hygiene, encourage physical activities, appropriate diet, and good sleep habits, and integrate such health promotion materials into the school curriculum. 3 A Chinese child studies from home during the COVID-19 outbreak © 2020 Fan Jiang 2020 Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. In the event of home confinement, parents are often the closest and best resource for children to seek help from. Close and open communication with children is the key to identifying any physical and psychological issues and to comforting children in prolonged isolation.10, 11 Parents are often important role models in healthy behaviour for children. Good parenting skills become particularly crucial when children are confined at home. Besides monitoring child performance and behaviour, parents also need to respect their identity and needs, and they need to help children develop self-discipline skills. Children are constantly exposed to epidemic-related news, so having direct conversations with children about these issues could alleviate their anxiety and avoid panic.10, 11 Home confinement could offer a good opportunity to enhance the interaction between parents and children, involve children in family activities, and improve their self-sufficiency skills. With the right parenting approaches, family bonds can be strengthened, and child psychological needs met. 12 Since the COVID-19 epidemic is no longer confined to China, 13 school closure and home confinement-related issues also become relevant in other affected countries. As children are vulnerable to environmental risks and their physical health, mental health, and productivity in adult life is deeply rooted in early years, 14 close attention and great efforts are required to address these emergency issues effectively and avoid any long-term consequences in children. Any sustainable programme must involve local professionals to culturally adapt the interventions to the administrative system and to the regional and community environment, and it must develop contextually relevant material for children and adolescents. 7 Finally, children have little voices to advocate for their needs. The latest Commission 14 on the future of the world's children urges a holistic strategy in preparing for the uncertainty that all children are facing. It is the responsibility and keen interests of all stakeholders, from governments to parents, to ensure that the physical and mental impacts of the COVID-19 epidemic on children and adolescents are kept minimal. Immediate actions are warranted.
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              Impact of COVID-19 pandemic on children and adolescents' lifestyle behavior larger than expected

              To the Editor: The ongoing coronavirus disease 2019 (COVID-19) spread is a public health emergency and global threat. Governments have ordered citizens to stay at home as an emergency measure and implemented school closures to prevent further spread of the infection. As of March 26, 2020, >150 million children and adolescents in 165 countries are affected by the closures. 1 Under such situations, physical and mental health problems are significant concerns. Particularly, children and adolescents' lifestyle behaviors, such as physical activity (PA) and sedentary behavior (SB) may have been drastically impacted due to the prolonged school closures and home confinement during the COVID-19 pandemic. It is well-known that reduced PA and prolonged SB are linked to both negative physical and mental health outcomes, 2 such as loss of muscular and cardiorespiratory fitness, weight gain, 3 psychosocial problems, 4 and even poor academic achievements. 5 Furthermore, evidence suggests that the negative impact may extend to adulthood. 6 Nonetheless, >70% of 1.6 million adolescents failed to achieve sufficient PA globally in 2016. 7 The current COVID-19 pandemic may further worsen this situation. Thus, a better understanding of the current situation of PA and SB during this pandemic among children and adolescents could help teachers, parents, and the Ministry of Education to urgently determine and implement effective policies and interventions for children and adolescents. However, till date, no study examined this issue. Therefore, we probed this aspect in detail during this critical time. We conducted a natural experimental longitudinal study among children and adolescents (6–17 years) in five schools in Shanghai, China, randomly selected from five districts with a high population density. The first survey was conducted from 3 to 21 January 2020 (Public health emergency was activated in Shanghai since January 24, 2020) and the second survey from 13 to 23 March 2020 (during the pandemic). In total, 2427 children and adolescents participated in the two surveys. Moderate- and vigorous-intensity PA was measured based on Global Physical Activity Questionnaire (GPAQ) developed by the World Health Organization. PA was calculated as weekly minutes of moderate-intensity PA plus twice the reported minutes of vigorous-intensity PA and was defined as inactive ( 2 h/day). Analyses were conducted using SPSS version 25. We analyzed data from 2426 children and adolescents (boys, 51.2%; girls, 48.8%) with valid data on PA and SB. Overall, the median time spent in PA decreased drastically, from 540 min/week (before the pandemic) to 105 min/week (during the pandemic), yielding 435 min reduction on average. Of note, during the pandemic, prevalence of physically inactive students extensively increased from 21.3% to 65.6%. Screen time considerably increased during the pandemic in total (+1730 min [or approximately 30 h] per week on average). Screen time during leisure was also prolonged, indicating that nearly a quarter of students engaged in long screen time for leisure. These data revealed a substantial decrease in PA and increase in screen time during the COVID-19 pandemic. The new coronavirus is still spreading globally, which may have the lasting impact on PA patterns and sedentary time, 8 posing severe challenges for children and adolescents as well. The reduced PA and prolonged SB may negatively impact children's and adolescents' physical and mental health, and in turn, such worsened health conditions would further reduce PA level and prolong SB. Such a vicious circle should thus be broken. Additionally, the evidence suggests that PA provides protection from viral infections, especially among vulnerable populations. 9 Therefore, governments, schools, professionals for health and exercise, and parents need to be aware of the severe situation and implement more effective interventions for PA immediately to minimize the negative impact of the COVID-19 pandemic on children's and adolescents' health (Table 1 ). Table 1 Physical activity and sedentary time before and during the COVID-19 pandemic among children and adolescents in China. Table 1 Total (n = 2426) Before the pandemic During the pandemic Absolute change P valuea Physical activity (min/week) 540 105 −435 2 h/day) 7.3% 30.9% +23.6% Data are shown as median or percentages. a Calculated using Wilcoxon test or Chi-squared test. b Defined as <30 min/day, whereas ≥30 and <60 min/day for insufficient physical activity and ≥60 min/day for sufficient physical activity. Funding and ethics approval This research was funded by the 10.13039/501100001809 National Natural Science Foundation of China (grant number 71804110) for Mi Xiang. The study protocol was approved by the Ethics Committee of Shanghai Jiaotong University School of Medicine (SJUPN-201813). The funding body had no role in the present study. Declaration of competing interest There is no conflict of interest of any authors with regard to this publication.
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                Author and article information

                Contributors
                Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole: Project administrationRole: SupervisionRole: VisualizationRole: Writing – original draftRole: Writing – review & editing
                Role: Data curationRole: Funding acquisitionRole: Project administrationRole: SupervisionRole: VisualizationRole: Writing – review & editing
                Role: Data curationRole: Formal analysisRole: VisualizationRole: Writing – review & editing
                Role: Data curationRole: Investigation
                Role: Data curationRole: Formal analysisRole: Methodology
                Role: ConceptualizationRole: Data curationRole: InvestigationRole: MethodologyRole: ResourcesRole: SoftwareRole: SupervisionRole: ValidationRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS One
                plos
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                21 March 2022
                2022
                21 March 2022
                : 17
                : 3
                : e0262166
                Affiliations
                [1 ] Department of Ophthalmology, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical university, Xuzhou, Jiangsu Province, China
                [2 ] Xuzhou Medical University, Xuzhou, Jiangsu Province, China
                [3 ] The Primary and Middle School Health Care Center in Suqian, Suqian, Jiangsu Province, China
                [4 ] School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu Province, China
                National Yang-Ming University Hospital, TAIWAN
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                ‡ YL, WZ, LD and WW also contributed equally to this work.

                Author information
                https://orcid.org/0000-0002-3986-8814
                Article
                PONE-D-21-27129
                10.1371/journal.pone.0262166
                8937315
                35312694
                23a1c2e7-a166-4c32-949c-04938212d688
                © 2022 Chen et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 5 September 2021
                : 19 December 2021
                Page count
                Figures: 1, Tables: 3, Pages: 12
                Funding
                Funded by: Science and Technology Development of Clinical Medicine of Jiangsu University in 2021
                Award ID: JLY2021179
                Award Recipient :
                Funded by: Science and Technology Project of Xuzhou
                Award ID: KC21278
                Award Recipient :
                This study was supported by the Project source "Science and Technology Development of Clinical Medicine of Jiangsu University in 2021, JLY2021179, Xiao Juan Wang” and “Science and Technology Project of Xuzhou, KC21278, Xiao Juan Wang”.
                Categories
                Research Article
                Medicine and Health Sciences
                Ophthalmology
                Visual Impairments
                Myopia
                Social Sciences
                Sociology
                Education
                Schools
                Medicine and Health Sciences
                Medical Conditions
                Infectious Diseases
                Viral Diseases
                Covid 19
                Medicine and Health Sciences
                Epidemiology
                Pandemics
                People and Places
                Population Groupings
                Age Groups
                Children
                People and Places
                Population Groupings
                Families
                Children
                People and Places
                Population Groupings
                Age Groups
                Children
                Adolescents
                People and Places
                Population Groupings
                Families
                Children
                Adolescents
                Research and Analysis Methods
                Research Design
                Cross-Sectional Studies
                Biology and Life Sciences
                Neuroscience
                Cognitive Science
                Cognitive Psychology
                Perception
                Sensory Perception
                Vision
                Visual Acuity
                Biology and Life Sciences
                Psychology
                Cognitive Psychology
                Perception
                Sensory Perception
                Vision
                Visual Acuity
                Social Sciences
                Psychology
                Cognitive Psychology
                Perception
                Sensory Perception
                Vision
                Visual Acuity
                Biology and Life Sciences
                Neuroscience
                Sensory Perception
                Vision
                Visual Acuity
                Custom metadata
                All relevant data are within the manuscript and its Supporting information files.
                COVID-19

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