The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

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Abstract

Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the pathobiology (changes in organ function, morphology, cell biology, biochemistry, immunology, and circulation), management, and epidemiology of sepsis, suggesting the need for reexamination.

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Journal

Journal ID (iso-abbrev): JAMA

Title: JAMA

Publisher: American Medical Association (AMA)

ISSN (Electronic): 1538-3598

ISSN (Print): 0098-7484

Publication date (Electronic): Feb 23 2016

Volume: 315

Issue: 8

Affiliations

[1 ] Bloomsbury Institute of Intensive Care Medicine, University College London, London, United Kingdom.

[2 ] Hofstra-Northwell School of Medicine, Feinstein Institute for Medical Research, New Hyde Park, New York.

[3 ] Department of Critical Care and Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

[4 ] Department of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

[5 ] Department of Critical Care Medicine, University of Versailles, France.

[6 ] Center for Sepsis Control and Care, University Hospital, Jena, Germany.

[7 ] Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, and Austin Hospital, Melbourne, Victoria, Australia.

[8 ] Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University, Nashville, Tennessee.

[9 ] Réanimation Médicale-Hôpital Cochin, Descartes University, Cochin Institute, Paris, France.

[10 ] Critical Care Center, Emory University School of Medicine, Atlanta, Georgia.

[11 ] Washington University School of Medicine, St Louis, Missouri.

[12 ] Infectious Disease Section, Division of Pulmonary and Critical Care Medicine, Brown University School of Medicine, Providence, Rhode Island.

[13 ] Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

[14 ] Emory University School of Medicine and Grady Memorial Hospital, Atlanta, Georgia.

[15 ] Trauma, Emergency & Critical Care Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada16Interdepartmental Division of Critical Care, University of Toronto.

[16 ] Department of Infectious Diseases, Academisch Medisch Centrum, Amsterdam, the Netherlands.

[17 ] Department of Intensive Care, Erasme University Hospital, Brussels, Belgium.

[18 ] Department of Critical Care Medicine, University of Pittsburgh and UPMC Health System, Pittsburgh, Pennsylvania20Associate Editor, JAMA.

Article

Mid ID: NIHMS794087 Publisher Item ID: 2492881

DOI: 10.1001/jama.2016.0287

PMC ID: 4968574

PubMed ID: 26903338

SO-VID: 8f991778-7327-4723-9ac1-61a2668e0212

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