Indocyanine green angiography of acute multifocal posterior placoid pigment epitheliopathy.

To understand the pathophysiology of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE). Indocyanine green (ICG) angiography was used for three patients, four eyes with acute AMPPPE and four eyes with healed AMPPPE. The angiographic photographs demonstrated widespread choroidal hypofluorescence of the active and healed lesions. Although the pathogenesis and histopathology of AMPPPE are unknown, the literature suggests that AMPPPE may represent an inflammatory reaction, possibly a delayed-type hypersensitivity reaction. The ICG choroidal hypofluorescence in AMPPPE is probably due to partial choroidal vascular occlusion secondary to occlusive vasculitis.