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      Motion, Relation, and Passion in Brain Physiological and Cognitive Aging

      , ,
      Brain Sciences
      MDPI AG

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          Abstract

          The aim of the current paper was to present important factors for keeping the basic structures of a person’s brain function, i.e., the grey and white matter, intact. Several lines of evidence have shown that motion, relation, and passion are central factors for preserving the neural system in the grey and white matter during ageing. An active lifestyle has shown to contribute to the development of the central nervous system and to contrast brain ageing. Interpersonal relationships, and interactions, have shown to contribute to complex biological factors that benefit the cognitive resilience to decline. Furthermore, the current scientific literature suggests that passion, strong interest, could be the driving factor motivating individuals to learn new things, thus influencing the development and maintenance of the neural functional network over time. The present theoretical perspective paper aims to convey several key messages: (1) brain development is critically affected by lifestyle; (2) physical training allows one to develop and maintain brain structures during ageing, and may be one of the keys for good quality of life as an older person; (3) diverse stimuli are a key factor in maintaining brain structures; (4) motion, relation, and passion are key elements for contrasting the loss of the grey and white matter of the brain.

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          Dementia prevention, intervention, and care

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            Principles of experience-dependent neural plasticity: implications for rehabilitation after brain damage.

            This paper reviews 10 principles of experience-dependent neural plasticity and considerations in applying them to the damaged brain. Neuroscience research using a variety of models of learning, neurological disease, and trauma are reviewed from the perspective of basic neuroscientists but in a manner intended to be useful for the development of more effective clinical rehabilitation interventions. Neural plasticity is believed to be the basis for both learning in the intact brain and relearning in the damaged brain that occurs through physical rehabilitation. Neuroscience research has made significant advances in understanding experience-dependent neural plasticity, and these findings are beginning to be integrated with research on the degenerative and regenerative effects of brain damage. The qualities and constraints of experience-dependent neural plasticity are likely to be of major relevance to rehabilitation efforts in humans with brain damage. However, some research topics need much more attention in order to enhance the translation of this area of neuroscience to clinical research and practice. The growing understanding of the nature of brain plasticity raises optimism that this knowledge can be capitalized upon to improve rehabilitation efforts and to optimize functional outcome.
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              Practice guideline update summary: Mild cognitive impairment

              To update the 2001 American Academy of Neurology (AAN) guideline on mild cognitive impairment (MCI).
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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                BSRCCS
                Brain Sciences
                Brain Sciences
                MDPI AG
                2076-3425
                September 2022
                August 24 2022
                : 12
                : 9
                : 1122
                Article
                10.3390/brainsci12091122
                930fd1f2-9282-4118-9c93-bfdbed857d07
                © 2022

                https://creativecommons.org/licenses/by/4.0/

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