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Predictive value of p53 and pRb expression in superficial bladder cancer patients treated with BCG and interferon-alpha.
Kesavan Esuvaranathan
1 ,
Edmund Chiong ,
Thomas Paulraj Thamboo ,
Yiong Huak Chan ,
Revathi Kamaraj ,
Ratha Mahendran ,
Ming Teh
Mar 15 2007
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Abstract
Nuclear p53 and retinoblastoma protein (pRb) were reported to be poor prognostic indicators for transitional cell carcinoma of the bladder. The authors sought to determine the prognostic value of nuclear p53 and pRb in superficial bladder transitional cell carcinoma patients who were treated with intravesical bacille Calmette-Guerin (BCG) or BCG with interferon-alpha (IFN-alpha).