[1
]Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New
York, NY, USA.
[2
]Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
[3
]Division of Newborn Medicine, Boston Children’s Hospital, Boston, MA, USA.
[4
]Department of Genetics, Harvard Medical School, Boston, MA, USA.
[5
]Departments of Systems Biology and Biomedical Informatics, Columbia University, New
York, NY, USA.
[6
]Flatiron Institute, Simons Foundation, New York, NY, USA.
[7
]Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton,
NJ, USA.
[8
]Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center,
Dallas, TX, USA.
[9
]Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai,
New York, NY, USA.
[10
]Center for External Innovation, Takeda Pharmaceuticals USA, Cambridge, MA, USA.
[11
]Sema4, a Mount Sinai venture, Stamford, CT, USA.
[12
]Department of Human Genetics, Utah Center for Genetic Discovery, University of Utah
School of Medicine, Salt Lake City, UT, USA.
[13
]Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount
Sinai, New York, NY, USA.
[14
]Heart Development and Structural Diseases Branch, Division of Cardiovascular Sciences,
NHLBI/NIH, Bethesda, MD, USA.
[15
]Boston Children’s Hospital, Boston, MA, USA.
[16
]Cardiorespiratory Unit, Great Ormond Street Hospital, London, UK.
[17
]Division of Cardiology, Children’s Hospital of Philadelphia, PA, USA.
[18
]Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania,
Philadelphia, PA, USA.
[19
]Departments of Pediatrics and Genetics, Yale University School of Medicine, New Haven,
CT, USA.
[20
]Children’s Hospital Los Angeles, Los Angeles, CA, USA.
[21
]Department of Pediatrics, University of Rochester, Rochester, NY, USA.
[22
]Department of Pediatrics, Stanford University, Palo Alto, CA, USA.
[23
]Departments of Pediatrics and Medicine, Columbia University Medical Center, New York,
NY, USA.
[24
]Gladstone Institute of Cardiovascular Disease and University of California San Francisco,
San Francisco, CA, USA.
[25
]Division of Pediatric Cardiology, University of Utah School of Medicine, Salt Lake
City, UT, USA.
[26
]Department of Computer Science, Princeton University, Princeton, NJ, USA.
[27
]Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Lab,
Berkeley, CA, USA.
[28
]Department of Cardiology, Brigham and Women’s Hospital, Boston, MA, USA.
[29
]Mindich Child Health and Development Institute, Icahn School of Medicine at Mount
Sinai, New York, NY, USA.
[30
]Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[31
]These authors contributed equally to this work.
[32
]These authors jointly directed this project.
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