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      Catheter ablation for ventricular tachycardia in patients with cardiac sarcoidosis: a systematic review.

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          Abstract

          Cardiac sarcoidosis (CS) is associated with a poor prognosis. Important features of CS include heart failure, conduction abnormalities, and ventricular arrhythmias. Ventricular tachycardia (VT) is often refractory to antiarrhythmic drugs (AAD) and immunosuppression. Catheter ablation has emerged as a treatment option for recurrent VT. However, data on the efficacy and outcomes of VT ablation in this context are sparse.

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          Cardiac sarcoidosis: epidemiology, characteristics, and outcome over 25 years in a nationwide study.

          Kari Kaikkonen, Markus Pelkonen, Jorma O. Kokkonen … (2015)
          This study was designed to assess the epidemiology, characteristics, and outcome of cardiac sarcoidosis (CS) in Finland.
          Article 0 comments Cited 163 times – based on 0 reviews     Review now
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            Cardiac sarcoidosis: a comprehensive review

            Vishal Sekhri, Shireen Sanal, Lawrence DeLorenzo … (2011)
            Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by noncaseating granulomas in involved organs. Organs involved with sarcoidosis include lymph nodes, skin, lung, central nervous system, and eye. Only 40-50% of patients with cardiac sarcoidosis diagnosed at autopsy have the diagnosis made during their lifetime. Cardiac sarcoidosis can manifest itself as complete heart block, ventricular arrhythmias, congestive heart failure, pericardial effusion, pulmonary hypertension, and ventricular aneurysms. Diagnostic tests such as the electrocardiogram, two-dimensional echocardiography, cardiac magnetic resonance imaging, positron emission tomography scan, radionuclide scan, and endomyocardial biopsy can be helpful in the early detection of cardiac sarcoidosis. Considering the increased risk of sudden death, cardiac sarcoidosis is an indication for early treatment with corticosteroids or other immunosuppressive agents. Other treatments include placement of a pacemaker or implantable defibrillator to prevent sudden death. In refractory cases, cardiac transplantation should be considered.
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              Ventricular tachycardia in cardiac sarcoidosis: characterization of ventricular substrate and outcomes of catheter ablation.

              Saurabh Kumar, Chirag Barbhaiya, Koichi Nagashima … (2015)
              Cardiac sarcoid-related ventricular tachycardia (VT) is a rare disorder; the underlying substrate and response to ablation are poorly understood. We sought to examine the ventricular substrate and outcomes of catheter ablation in this population.
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                Author and article information

                Journal
                Journal ID (iso-abbrev): Europace
                Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
                Publisher: Oxford University Press (OUP)
                ISSN (Electronic): 1532-2092
                ISSN (Print): 1099-5129
                Publication date (Electronic): April 01 2018
                Volume: 20
                Issue: 4
                Affiliations
                [1 ] Electrophysiology Department, Barts Heart Centre, St. Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK.
                [2 ] Institute of Cardiovascular Science, University College London, Gower St, London WC1E 6BT, UK.
                [3 ] Cardiology Department, Royal Brompton Hospital, Sydney St, SW3 6NP, London, UK.
                [4 ] Division of Electrophysiology, Department of Cardiovascular Medicine, University Hospital of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.
                Article
                Publisher Item ID: 3748228
                DOI: 10.1093/europace/eux077
                PubMed ID: 28444174
                SO-VID: bfddffc0-d016-4200-9320-da7e0a45094a
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