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      Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation.

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          Abstract

          Current guidelines recommend pulmonary-vein isolation by means of catheter ablation as treatment for drug-refractory paroxysmal atrial fibrillation. Radiofrequency ablation is the most common method, and cryoballoon ablation is the second most frequently used technology.

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          Most cited references9

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          Is Open Access

          Paroxysmal AF catheter ablation with a contact force sensing catheter: results of the prospective, multicenter SMART-AF trial.

          Catheter ablation is important for treatment of paroxysmal atrial fibrillation (PAF). Limited animal and human studies suggest a correlation between electrode-tissue contact and radiofrequency lesion generation.
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            Impact of Complete Versus Incomplete Circumferential Lines Around the Pulmonary Veins During Catheter Ablation of Paroxysmal Atrial Fibrillation: Results From the Gap-Atrial Fibrillation-German Atrial Fibrillation Competence Network 1 Trial.

            Ablation of atrial fibrillation (AF) is an established treatment option for symptomatic patients. It is not known whether complete pulmonary vein isolation (PVI) is superior to incomplete PVI with regard to the patients' clinical outcome.
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              Durability of Pulmonary Vein Isolation with Cryoballoon Ablation: Results from the Sustained PV Isolation with Arctic Front Advance (SUPIR) Study.

              Pulmonary vein (PV) reconnection remains the most important cause of AF recurrence after AF ablation. The second-generation cryoballoon catheter's ability to achieve durable PV isolation was assessed in a prospective nonrandomized clinical trial.
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                Author and article information

                Journal
                N. Engl. J. Med.
                The New England journal of medicine
                Massachusetts Medical Society
                1533-4406
                0028-4793
                Jun 09 2016
                : 374
                : 23
                Affiliations
                [1 ] From the Department of Cardiology, Asklepios Klinik St. Georg, Hamburg (K.-H.K., A.M., F.O.), Cardioangiologisches Centrum Bethanien, Medical Department III am Markus Krankenhaus, Frankfurt (A.F., J.C.), Herz-Zentrum, Bad Krozingen (T.A.), and Technische Universität Dresden, Dresden (K.B.) - all in Germany; Hospital Clinic, University of Barcelona, Barcelona (J.B.); Isala Klinieken, Zwolle, the Netherlands (A.E.); London School of Hygiene and Tropical Medicine, London (S.J.P.); Clinique Pasteur, Toulouse, France (J.-P.A.); and Centro Cardiologico Monzino, University of Milan, Milan (C.T.).
                Article
                10.1056/NEJMoa1602014
                27042964
                7f59be40-cc84-4350-aa05-11264e734a26
                History

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