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      Call for Papers: Sex and Gender in Neurodegenerative Diseases

      Submit here before January 31, 2025

      About Neurodegenerative Diseases: 1.9 Impact Factor I 5.9 CiteScore I 0.648 Scimago Journal & Country Rank (SJR)

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      Validation of the Addenbrooke's Cognitive Examination III in frontotemporal dementia and Alzheimer's disease.

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      Journal: Dementia and Geriatric Cognitive Disorders
      Keywords: Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, psychology, Attention, physiology, Cognition, Data Interpretation, Statistical, Female, Frontotemporal Dementia, Humans, Language, Male, Memory, Middle Aged, Neuropsychological Tests, Reproducibility of Results, Space Perception, Verbal Learning, Visual Perception, Wechsler Scales

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          Abstract

          The aims of this study were to validate the newly developed version of the Addenbrooke's Cognitive Examination (ACE-III) against standardised neuropsychological tests and its predecessor (ACE-R) in early dementia. A total of 61 patients with dementia (frontotemporal dementia, FTD, n = 33, and Alzheimer's disease, AD, n = 28) and 25 controls were included in the study. ACE-III cognitive domains correlated significantly with standardised neuropsychological tests used in the assessment of attention, language, verbal memory and visuospatial function. The ACE-III also compared very favourably with its predecessor, the ACE-R, with similar levels of sensitivity and specificity. The results of this study provide objective validation of the ACE-III as a screening tool for cognitive deficits in FTD and AD. © 2013 S. Karger AG, Basel.

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          Distinguishing Subtypes in Primary Progressive Aphasia: Application of the Sydney Language Battery

          Sharon Savage, S. Savage, Sharpley Hsieh … (2013)
          Background/Aims: Primary progressive aphasia (PPA) comprises three main subtypes, varying in clinical features, patterns of brain atrophy, and underlying pathology. Differentiation of these variants is important for treatment and planning; however, simple, effective cognitive tests to aid diagnosis are lacking. This study introduces a new language battery - the SYDBAT (Sydney Language Battery) - to assist clinicians. Methods: Fifty-seven PPA patients and 54 age- and education-matched healthy controls were compared on naming, repetition, word comprehension, and semantic association subtests. Results: Significant group differences were found for all tasks, reflecting different language profiles for each group. Using discriminative function analysis, 80% of PPA cases were correctly classified from three SYDBAT scores, from which a simple diagnostic algorithm was defined. Conclusion: The SYDBAT is a fast and simple tool which provides a valuable adjunct to clinicians diagnosing PPA.
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            The differentiation of semantic dementia and frontal lobe dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer's disease: A comparative neuropsychological study.

            John R. Hodges, Peter Garrard, Rose Marie Ward … (1999)
            Article 0 comments Cited 45 times – based on 0 reviews     Review now
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              The Rowland Universal Dementia Assessment Scale (RUDAS) and the Folstein MMSE in a multicultural cohort of elderly persons.

              David Conforti, Joella E Storey, Jeffrey Rowland … (2006)
              To compare the accuracy of the Rowland Universal Dementia Assessment Scale (RUDAS) and the Folstein Mini-mental State Examination (MMSE) for diagnosis of dementia in a multicultural cohort of elderly persons.
              Article 0 comments Cited 41 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                PubMed ID:: 23949210
                DOI:: 10.1159/000351671

                ScienceOpen disciplines: Chemistry
                Keywords: Aged,Aged, 80 and over,Alzheimer Disease,diagnosis,psychology,Attention,physiology,Cognition,Data Interpretation, Statistical,Female,Frontotemporal Dementia,Humans,Language,Male,Memory,Middle Aged,Neuropsychological Tests,Reproducibility of Results,Space Perception,Verbal Learning,Visual Perception,Wechsler Scales
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                ScienceOpen disciplines: Chemistry
                Keywords: Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, psychology, Attention, physiology, Cognition, Data Interpretation, Statistical, Female, Frontotemporal Dementia, Humans, Language, Male, Memory, Middle Aged, Neuropsychological Tests, Reproducibility of Results, Space Perception, Verbal Learning, Visual Perception, Wechsler Scales

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