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      Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.

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          Abstract

          To characterize further behavioral, cognitive, neuroendocrine, and physiological effects of subanesthetic doses of ketamine hydrochloride in healthy human subjects. Ketamine, a phencyclidine hydrochloride derivative, is a dissociative anesthetic and a noncompetitive antagonist of the N-methyl-D-aspartate subtype of excitatory amino acid receptor.

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          Author and article information

          Journal
          Arch Gen Psychiatry
          Archives of general psychiatry
          American Medical Association (AMA)
          0003-990X
          0003-990X
          Mar 1994
          : 51
          : 3
          Affiliations
          [1 ] Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.
          Article
          10.1001/archpsyc.1994.03950030035004
          8122957
          d28a0f85-a67e-4c9f-b542-7f9b7ad739b6
          History

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