Increased cortical surface area and gyrification following long-term survival from early monocular enucleation.

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Abstract

Retinoblastoma is typically diagnosed before 5 years of age and is often treated by enucleation (surgical removal) of the cancerous eye. Here, we sought to characterize morphological changes of the cortex following long-term survival from early monocular enucleation.

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Most cited references 78

Record: found
Abstract: found
Article: not found

Distributed and overlapping representations of faces and objects in ventral temporal cortex.

J Haxby, M. I. Gobbini, M. Furey … (2001)

The functional architecture of the object vision pathway in the human brain was investigated using functional magnetic resonance imaging to measure patterns of response in ventral temporal cortex while subjects viewed faces, cats, five categories of man-made objects, and nonsense pictures. A distinct pattern of response was found for each stimulus category. The distinctiveness of the response to a given category was not due simply to the regions that responded maximally to that category, because the category being viewed also could be identified on the basis of the pattern of response when those regions were excluded from the analysis. Patterns of response that discriminated among all categories were found even within cortical regions that responded maximally to only one category. These results indicate that the representations of faces and objects in ventral temporal cortex are widely distributed and overlapping.

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Record: found
Abstract: found
Article: not found

Specification of cerebral cortical areas.

P Rakic (1988)

How the immense population of neurons that constitute the human cerebral neocortex is generated from progenitors lining the cerebral ventricle and then distributed to appropriate layers of distinctive cytoarchitectonic areas can be explained by the radial unit hypothesis. According to this hypothesis, the ependymal layer of the embryonic cerebral ventricle consists of proliferative units that provide a proto-map of prospective cytoarchitectonic areas. The output of the proliferative units is translated via glial guides to the expanding cortex in the form of ontogenetic columns, whose final number for each area can be modified through interaction with afferent input. Data obtained through various advanced neurobiological techniques, including electron microscopy, immunocytochemistry, [3H]thymidine and receptor autoradiography, retrovirus gene transfer, neural transplants, and surgical or genetic manipulation of cortical development, furnish new details about the kinetics of cell proliferation, their lineage relationships, and phenotypic expression that favor this hypothesis. The radial unit model provides a framework for understanding cerebral evolution, epigenetic regulation of the parcellation of cytoarchitectonic areas, and insight into the pathogenesis of certain cortical disorders in humans.

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Record: found
Abstract: found
Article: not found

A tension-based theory of morphogenesis and compact wiring in the central nervous system.

D C Van Essen (1997)

Many structural features of the mammalian central nervous system can be explained by a morphogenetic mechanism that involves mechanical tension along axons, dendrites and glial processes. In the cerebral cortex, for example, tension along axons in the white matter can explain how and why the cortex folds in a characteristic species-specific pattern. In the cerebellum, tension along parallel fibres can explain why the cortex is highly elongated but folded like an accordion. By keeping the aggregate length of axonal and dendritic wiring low, tension should contribute to the compactness of neural circuitry throughout the adult brain.

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Author and article information

Journal

Journal ID (iso-abbrev): Neuroimage Clin

Title: NeuroImage. Clinical

Publisher: Elsevier BV

ISSN (Electronic): 2213-1582

ISSN (Print): 2213-1582

Publication date (Electronic): 2015

Volume: 7

Affiliations

[1 ] Department of Psychology, York University, Toronto, Canada ; Centre for Vision Research, York University, Toronto, Canada.

[2 ] Department of Ophthalmology and Visual Sciences, The Hospital for Sick Children, Toronto, Canada.

[3 ] Department of Psychology, York University, Toronto, Canada ; Centre for Vision Research, York University, Toronto, Canada ; Department of Ophthalmology and Visual Sciences, The Hospital for Sick Children, Toronto, Canada.

Article

Publisher Item ID: S2213-1582(14)00185-5

DOI: 10.1016/j.nicl.2014.11.020

PMC ID: 4300017

PubMed ID: 25610793

SO-VID: dd4428dd-1ad3-427c-b702-3c65aef41154

History

Keywords: Morphological development,Hemisphere asymmetry,Monocular enucleation,Visual cortex,Brain plasticity,Early visual deprivation

Data availability:

Keywords: Morphological development, Hemisphere asymmetry, Monocular enucleation, Visual cortex, Brain plasticity, Early visual deprivation

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