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      Time to Clinical Benefit of Intensive Blood Pressure Lowering in Patients 60 Years and Older With Hypertension : A Secondary Analysis of Randomized Clinical Trials

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          Abstract

          This secondary analysis of randomized clinical trials estimates the time needed to potentially derive clinical benefit from intensive blood pressure treatment in patients 60 years and older.

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          Most cited references43

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          2018 ESC/ESH Guidelines for the management of arterial hypertension

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            A Randomized Trial of Intensive versus Standard Blood-Pressure Control

            New England Journal of Medicine, 373(22), 2103-2116
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              2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults

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                Author and article information

                Journal
                JAMA Internal Medicine
                JAMA Intern Med
                American Medical Association (AMA)
                2168-6106
                May 09 2022
                Affiliations
                [1 ]Department of Public Health, Policy and Systems, Institute of Population Health, The University of Liverpool, Liverpool, United Kingdom
                [2 ]Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
                [3 ]Department of Biostatistics, School of Public Health, Nanjing Medical University, Jiangsu, Nanjing, China
                [4 ]Department of Cardiology, The First Affiliated Hospital of USTC, Hefei, China
                [5 ]Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China
                [6 ]Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Disease, Peking Union Medical College and Chinese Academy of Medical Sciences, Mentougou District, Beijing, China
                [7 ]Department of Geriatric Medicine, The University of Auckland, Auckland, New Zealand
                [8 ]Department of Epidemiology and Health Statistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, China
                [9 ]Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, United Kingdom
                [10 ]Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, China
                Article
                10.1001/jamainternmed.2022.1657
                43926f13-e12e-45d9-a67a-295dcb5ae1b6
                © 2022
                History

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