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      Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial.

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          Abstract

          Synovitis is common and is associated with progression of structural characteristics of knee osteoarthritis. Intra-articular corticosteroids could reduce cartilage damage associated with synovitis but might have adverse effects on cartilage and periarticular bone.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          1538-3598
          0098-7484
          May 16 2017
          : 317
          : 19
          Affiliations
          [1 ] Division of Rheumatology, Tufts Medical Center, Boston, Massachusetts.
          [2 ] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
          [3 ] Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts4Tufts Clinical and Translational Science Institute, Tufts University, Boston, Massachusetts.
          [4 ] Division of Musculoskeletal Imaging and Intervention, Tufts Medical Center, Boston, Massachusetts.
          Article
          2626573
          10.1001/jama.2017.5283
          28510679
          6d8a9ba5-f4cf-4cfa-bee8-c6f4e0010f36
          History

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