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      The protocols for the 10/66 dementia research group population-based research programme.

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          Abstract

          Latin America, China and India are experiencing unprecedentedly rapid demographic ageing with an increasing number of people with dementia. The 10/66 Dementia Research Group's title refers to the 66% of people with dementia that live in developing countries and the less than one tenth of population-based research carried out in those settings. This paper describes the protocols for the 10/66 population-based and intervention studies that aim to redress this imbalance.

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          Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization.

          Salim Yusuf, Srinath Reddy, Stephanie Ôunpuu … (2001)
          This two-part article provides an overview of the global burden of atherothrombotic cardiovascular disease. Part I initially discusses the epidemiologic transition which has resulted in a decrease in deaths in childhood due to infections, with a concomitant increase in cardiovascular and other chronic diseases; and then provides estimates of the burden of cardiovascular (CV) diseases with specific focus on the developing countries. Next, we summarize key information on risk factors for cardiovascular disease (CVD) and indicate that their importance may have been underestimated. Then, we describe overarching factors influencing variations in CVD by ethnicity and region and the influence of urbanization. Part II of this article describes the burden of CV disease by specific region or ethnic group, the risk factors of importance, and possible strategies for prevention.
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            Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop.

            G C Román, T K Tatemichi, T Erkinjuntti … (1993)
            Criteria for the diagnosis of vascular dementia (VaD) that are reliable, valid, and readily applicable in a variety of settings are urgently needed for both clinical and research purposes. To address this need, the Neuroepidemiology Branch of the National Institute of Neurological Disorders and Stroke (NINDS) convened an International Workshop with support from the Association Internationale pour la Recherche et l'Enseignement en Neurosciences (AIREN), resulting in research criteria for the diagnosis of VaD. Compared with other current criteria, these guidelines emphasize (1) the heterogeneity of vascular dementia syndromes and pathologic subtypes including ischemic and hemorrhagic strokes, cerebral hypoxic-ischemic events, and senile leukoencephalopathic lesions; (2) the variability in clinical course, which may be static, remitting, or progressive; (3) specific clinical findings early in the course (eg, gait disorder, incontinence, or mood and personality changes) that support a vascular rather than a degenerative cause; (4) the need to establish a temporal relationship between stroke and dementia onset for a secure diagnosis; (5) the importance of brain imaging to support clinical findings; (6) the value of neuropsychological testing to document impairments in multiple cognitive domains; and (7) a protocol for neuropathologic evaluations and correlative studies of clinical, radiologic, and neuropsychological features. These criteria are intended as a guide for case definition in neuroepidemiologic studies, stratified by levels of certainty (definite, probable, and possible). They await testing and validation and will be revised as more information becomes available.
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              Subjective burden of husbands and wives as caregivers: a longitudinal study.

              S. H. Zarit, P. Todd, J Zarit (1986)
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                Author and article information

                Journal
                Journal ID (iso-abbrev): BMC Public Health
                Title: BMC public health
                Publisher: Springer Science and Business Media LLC
                ISSN (Electronic): 1471-2458
                ISSN (Print): 1471-2458
                Publication date (Electronic): Jul 20 2007
                Volume: 7
                Affiliations
                [1 ] King's College London, Health Service and Population Research Department, Section of Epidemiology, De Crespigny Park, London, UK. m.prince@iop.kcl.ac.uk
                Article
                Publisher Item ID: 1471-2458-7-165
                DOI: 10.1186/1471-2458-7-165
                PMC ID: 1965476
                PubMed ID: 17659078
                SO-VID: bbc17a23-dced-484e-be7d-cae25c6a2f20
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