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      Lycium barbarum polysaccharides: Extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review.

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          Abstract

          In the last decades, glycoconjugates from Lycium barbarum L. fruit (Goji berry) have received a great attention for their potential health-promoting effects. The present review includes a survey of extraction and purification methods of these bioactive molecules (L. barbarum polysaccharides, LBPs), along with a dissertation on the structural characterisation of the carbohydrate component. Furthermore, an overview of in vitro, in vivo and clinical studies concerning the hypoglycaemic and hypolipidaemic effects of isolated LBP fractions, is reported. The evidence suggests that these purified components of the Goji berry may be potentially useful as adjuvants in the treatment of diabetes and its correlated illnesses.

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          Author and article information

          Journal
          Food Chem
          Food chemistry
          Elsevier BV
          1873-7072
          0308-8146
          Jul 15 2018
          : 254
          Affiliations
          [1 ] Dipartimento di Medicina Sperimentale, Unità di Ricerca di Scienza dell'Alimentazione e Nutrizione Umana, Università degli Studi di Roma "La Sapienza", Viale del Policlinico, 155, 00161 Roma, Italy.
          [2 ] Dipartimento di Farmacia, Università "G. d'Annunzio" di Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy.
          [3 ] Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma "La Sapienza", Piazzale Aldo Moro, 5, 00185 Roma, Italy.
          [4 ] Dipartimento di Chimica e Tecnologie del Farmaco, Università degli Studi di Roma "La Sapienza", Piazzale Aldo Moro, 5, 00185 Roma, Italy. Electronic address: stefania.cesa@uniroma1.it.
          Article
          S0308-8146(18)30197-3
          10.1016/j.foodchem.2018.01.176
          29548467
          6a35b1e0-e851-46e2-8dad-f3f8b1269208
          History

          Lycium barbarum polysaccharides,Goji berry,Hypoglycaemic effects,Hypolipidaemic effects,Arabinogalactan proteins

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